human ADAMTS13 protein

BAX930 is a recombinant form of ADAMTS13; RefSeq NM_139025

Also Known As:

ADAMTS13 protein, human; ADAMTS-13 protein, human; BAX930; VWFCP protein, human; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13, human; vWF-cleaving protease, human; von Willebrand factor-cleaving protease, human; von Willebrand factor-degrading protease, human

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Adili, Reheman: 1 article (01/2019)
2.	Holinstat, Michael: 1 article (01/2019)
3.	Benamara, K: 1 article (01/2016)
4.	Dietrich, B: 1 article (01/2016)
5.	Horling, F: 1 article (01/2016)
6.	Höbarth, G: 1 article (01/2016)
7.	Höllriegl, W: 1 article (01/2016)
8.	Kopić, A: 1 article (01/2016)
9.	Muchitsch, E-M: 1 article (01/2016)
10.	Piskernik, C: 1 article (01/2016)

Related Diseases

1.	Thrombosis (Thrombus) 01/01/2019 - "Prophylactic treatment with recombinant ADAMTS13 (BAX930) effectively prevented the onset of the VWF-mediated microvascular thrombosis and therapeutic treatment with BAX930 acutely resolved the preexisting or growing thrombi in the brain of ADAMTS13-/- mice after rVWF challenge. " 01/01/2019 - "The absence of platelet activation and fibrin formation within VWF-mediated thrombi and efficacy of BAX930 was confirmed with an endothelial-driven VWF-mediated microvascular thrombosis model in mice. "
2.	Thrombotic Thrombocytopenic Purpura 01/01/2016 - "Preclinical assessment of a new recombinant ADAMTS-13 drug product (BAX930) for the treatment of thrombotic thrombocytopenic purpura."

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