|1.||Fontana, Joseph A: 3 articles (07/2004 - 07/2002)|
|2.||Farhana, Lulu: 3 articles (07/2004 - 07/2002)|
|3.||Rishi, Arun K: 3 articles (07/2004 - 07/2002)|
|4.||Dawson, M I: 3 articles (06/2001 - 05/2000)|
|5.||Zhang, Xiao-kun: 2 articles (01/2007 - 11/2003)|
|6.||Peterson, Valerie J: 2 articles (07/2004 - 11/2003)|
|7.||Leid, Mark: 2 articles (07/2004 - 11/2003)|
|8.||Dawson, Marcia I: 2 articles (07/2004 - 11/2003)|
|9.||Zhang, Yuxiang: 2 articles (11/2003 - 07/2002)|
|10.||Zhang, Y: 2 articles (06/2001 - 05/2000)|
|1.||Lung Neoplasms (Lung Cancer)
08/01/1998 - "Together, our results reveal a novel pathway for retinoid-induced apoptosis and suggest that AHPN/CD437 or analogs may have a better therapeutic efficacy against lung cancer."
08/01/1998 - "In this study, we investigated the role of AHPN/CD437 and its mechanism of action in human lung cancer cell lines. "
08/01/1998 - "In addition, we found that expression of p53 and Bcl-2 was differentially regulated by AHPN/CD437 in different lung cancer cell lines and may play a role in regulating AHPN/CD437-induced apoptotic process. "
08/01/1998 - "Our results demonstrated that AHPN/CD437 effectively inhibited lung cancer cell growth by inducing G0/G1 arrest and apoptosis, a process that is accompanied by rapid induction of c-Jun, nur77, and p21(WAF1/CIP1). "
08/01/1998 - "Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines."
|3.||Human Influenza (Influenza)
01/01/2014 - "The application of AHPN restricted both the proliferative and infiltrative component in chronic post-influenza lesions. "
01/01/2014 - "In the present work the efficacy of the use of apoptosis inducer 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalenecarboxylic acid (AHPN) for prophylaxis of chronic damage on the stage of post- influenza pneumonia has been studied. "
04/01/2001 - "Induction of Egr-1 expression by the retinoid AHPN in human lung carcinoma cells is dependent on activated ERK1/2."
10/01/2000 - "Our results suggest that in ovarian carcinomas, AHPN/CD437 induced apoptosis is mediated at least in part via an RAR pathway."
05/15/2000 - "Moreover, AHPN (CD437) was unable to compete with either tRA or 9-cis-RA for binding to endogenous retinoid receptors in nuclear extracts from the MDA-MB-468 breast carcinoma cell line. "
02/15/1999 - "Growth inhibition and various regulatory responses were investigated in two human prostate carcinoma cell lines (LNCaP and PC-3) treated with or without a synthetic retinoid, CD 437. "
03/01/1998 - "Our results suggest that the growth inhibition of certain lung carcinoma cell lines by AHPN is at least partly related to an increase in p21. "
|5.||T-Cell Lymphoma (Lymphoma, T Cell)
04/01/2001 - "Overexpression of Bcl-2, which inhibits AHPN-induced apoptosis but not growth arrest in human T cell lymphoma Molt-4 cells, did not block the induction of immediate-early gene expression. "
11/01/1998 - "Induction of apoptosis by the novel retinoid AHPN in human T-cell lymphoma cells involves caspase-dependent and independent pathways."
11/01/1998 - "In this study, we show that the induction of growth arrest and apoptosis in a variety of T-cell lymphoma cell lines, including Jurkat and Molt-4 cells, is highly specific for the synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (AHPN) since all-trans retinoic acid (RA), the RAR-selective retinoid TTAB, the RXR-selective retinoid SR11217 and the retinoid SR11302 exhibiting selective anti-AP1 activity, do not induce apoptosis or cause growth arrest. "
|2.||Tretinoin (Retinoic Acid)
|6.||Retinoic Acid Receptors (Retinoic Acid Receptor)
|7.||Messenger RNA (mRNA)
|9.||Choline (Choline Chloride)
|10.||retinoic acid receptor gamma