HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

S 28463

structure given in first source

Also Known As:

4-amino-2-ethoxymethyl-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinoline-1-ethanol; S-28463

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Aminoquinolines: 29
        S 28463: 5

Experts

1.	Boghdady, M L: 1 article (05/2006)
2.	Camateros, P: 1 article (05/2006)
3.	Ding, A: 1 article (05/2006)
4.	Gaestel, M: 1 article (05/2006)
5.	Guiot, M C: 1 article (05/2006)
6.	Koohsari, H: 1 article (05/2006)
7.	Marion, D: 1 article (05/2006)
8.	Martin, J G: 1 article (05/2006)
9.	Martin, P: 1 article (05/2006)
10.	Moisan, J: 1 article (05/2006)

Related Diseases

1.	Neoplasms (Cancer) 05/01/1998 - "Imiquimod, and its analogs R-842, S-27609, and S-28463, are potent anti-viral and anti-tumor agents in animal models. "
2.	Necrosis 11/01/1997 - "Tumour necrosis factor alpha (TNF-alpha) was also increased in cultures stimulated with S-27609 or S-28463. "
3.	Leishmaniasis 06/01/1999 - "Treatment of experimental leishmaniasis with the immunomodulators imiquimod and S-28463: efficacy and mode of action."
4.	Infections 11/01/1995 - "S-28463 showed potent antiviral activity against herpes simplex virus-challenged guinea pigs when given subcutaneously, dermally, or intravaginally 24 h before infection. "
5.	Condylomata Acuminata (Genital Wart) 05/01/1998 - "These results demonstrate that imiquimod and S-28463 stimulate production of cytokines in the skin after topical application, which may play a major role in its activity in genital wart patients."

Related Drugs and Biologics

1.	Imiquimod (Aldara)
2.	4- amino- alpha,alpha,2- trimethyl- 1H- imidazo(4,5- c)quinoline- 1- ethanol
3.	Toll-Like Receptor 7
4.	Methacholine Chloride (Methacholine)
5.	Cytokines
6.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
7.	Ovalbumin
8.	Ligands
9.	Immunologic Factors (Immunomodulators)
10.	Antiviral Agents (Antivirals)