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semaphorin IV

nerve growth cone guidance signal; amino acid sequence in first source; GenBank U32172 (clone H1.47) and U32171 (clone H2.6)

Also Known As:

H-Sema IV

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - Nerve Growth Factors: 5035
      - semaphorin IV: 2
  - Nerve Tissue Proteins: 2
    - Nerve Growth Factors: 5035
      - semaphorin IV: 2
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - Nerve Growth Factors: 5035
      - semaphorin IV: 2
Biological Factors: 2472
- Intercellular Signaling Peptides and Proteins: 29768
  - Nerve Growth Factors: 5035
    - semaphorin IV: 2

Related Diseases

1.	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 04/30/1996 - "We have identified two additional members of the human semaphorin family [human semaphorin A(V) and human semaphorin IV] in chromosome region 3p21.3, where several small cell lung cancer (SCLC) cell lines exhibit homozygous deletions indicative of a tumor suppressor gene. "
2.	Paralysis (Palsy) 09/15/1999 - "Expression of this variant in cultured primary sympathetic neurons blocks the paralysis of growth cone motility normally induced by SEMA-3A (collapsin-1, semaphorin III, semaphorin D) and SEMA-3C (collapsin-3, semaphorin E) but not that induced by SEMA-3F (semaphorin IV). "

Related Drugs and Biologics

1.	Semaphorins (Semaphorin)
2.	Semaphorin-3A
3.	semaphorin A(V)