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heptavalent pneumococcal conjugate vaccine (Prevnar)

contains 7 pneumococcal serotypes (6B, 14, 19F, 23F, 18C, 4, 9V), each conjugated individually to the outer membrane protein complex of Neisseria meningitidi
Also Known As:
Prevnar; Prevenar; 7-valent PncOMPC vaccine; PNCRM7; seven-valent pneumococcal PS-meningococcal OMPC conjugate vaccine
Networked: 130 relevant articles (8 outcomes, 24 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Mason, Edward O: 4 articles (11/2011 - 12/2004)
2. Lewis, Edwin: 4 articles (09/2006 - 09/2002)
3. Ray, Paula: 4 articles (09/2006 - 09/2002)
4. McGowan, Karin L: 3 articles (12/2013 - 04/2003)
5. Shah, Samir S: 3 articles (03/2011 - 04/2003)
6. Nuorti, J Pekka: 3 articles (12/2010 - 09/2006)
7. Varon, E: 3 articles (11/2010 - 03/2007)
8. Cohen, R: 3 articles (08/2009 - 03/2007)
9. Principi, Nicola: 3 articles (01/2009 - 06/2003)
10. Hansen, John: 3 articles (09/2006 - 09/2002)

Related Diseases

1. Otitis Media
2. Pneumonia (Pneumonitis)
3. Bacteremia
4. Tetanus
03/01/2007 - "Vaccination resulted in a significant increase (P < or = .05) in antibody levels to each vaccine antigen studied, with 100% of patients achieving protection against tetanus (GMC, 2.2 IU/mL; 95% CI, 1.8-2.7 IU/mL), 100% achieving protection against Hib (GMC, 8.4 microg/mL; 95% CI, 7.6-9.3 microg/mL), 100% achieving protection against measles (GMC, 2435 mIU/mL; 95% CI, 1724-3439 mIU/mL), 100% achieving protection against meningococcus C (GMT, 1:5706; 95% CI, 1:3510-1:9272), 92% achieving protection against the 3 poliovirus serotypes, and > or = 80% achieving protection against each of the heptavalent pneumococcal conjugate vaccine-associated serotypes. "
01/01/2014 - "Safety and immunogenicity of a toddler dose following an infant series of a hexavalent diphtheria, tetanus, acellular pertussis, inactivated poliovirus, Haemophilus influenzae type b, hepatitis B vaccine administered concurrently or at separate visits with a heptavalent pneumococcal conjugate vaccine."
09/01/2011 - "The patient mounted adequate antibody responses to the protein-conjugated Prevnar and tetanus vaccines but not to the polysaccharide antigen based Pneumovax vaccine. "
01/01/2009 - "One study (120 children) found that when diphtheria-polio-tetanus-acellular pertussis-Haemophilus influenzae type b (DPTaP-Hib; Pentacel) and pneumococcus (Prevnar) were injected sequentially during the same office visit, observer- and parent-reported pain scores were lower when DPTaP-Hib was injected first (SMD, -0.40 and -0.57, respectively; P <or= 0.03). "
01/01/2012 - "We report the case of a 6-month-old infant who developed subcutaneous nodules at the sites of his 4- and 6-month Pentacel (DTaP/Hib/IPV, diphtheria, tetanus, acellular pertussis, Haemophilus b conjugate, and inactivated poliovirus vaccine) and 6-month Prevnar (heptavalent pneumococcal vaccine) injections. "
5. Fever (Fevers)

Related Drugs and Biologics

1. heptavalent pneumococcal conjugate vaccine (Prevnar)
2. Antigens
3. Vaccines
4. CRM197 (non-toxic variant of diphtheria toxin)
5. Pneumococcal Vaccines (Pneumococcal Polysaccharide Vaccine)
6. Diphtheria-Tetanus-acellular Pertussis Vaccines (Tripedia)
7. Antibodies
8. pentacel
9. Tetanus Toxoid (Vaccine, Tetanus)
10. Immunoglobulins (Immunoglobulin)

Related Therapies and Procedures

1. Middle Ear Ventilation (Tympanostomy)
2. Injections
3. Antibiotic Prophylaxis