dexelvucitabine

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4 relevant articles (0 outcomes, 1 trials/studies) found for this Bio-Agent

Description: inhibits human hepatitis B virus (HBV) and human immunodeficiency virus (HIV) in vitro; D4FC-TP is the triphosphate form

Also Known As:

2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine; 2',3'-dideoxy-2',3'-didehydro-beta-D-5-fluorocytidine; 2',3'-dideoxy-2',3'-didehydro-beta-L-5-fluorocytidine; 2(1H)-Pyrimidinone, 4-amino-1-((2S,5R)-2,5-dihydro-5-(hydroxymethyl)-2-furanyl)-5-fluoro-; 4-amino-5-fluoro-1-((2S,5R)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl)pyrimidin-2(1H)-one; ACH-126-443; DPC 817; DPC-817; DPC817; INCB-8721; Reverset; YZ-817; beta-L-Fd4C; elvucitabine

Bio-Agent Context: Research Results

Related Diseases

1.	Infection 12/01/2002 - "BACKGROUND: Our aim was to evaluate the anti-HBV activity of a novel L-nucleoside analog, 2',3'-dideoxy-2',3'-didehydro-beta-L-5-fluorocytidine (beta-L-Fd4C), in study models of HBV infection" 01/01/2000 - "Our data, therefore, demonstrate that in the duck model of HBV infection, beta-L-Fd4C is a potent inhibitor of DHBV reverse transcriptase activity in vitro and suppresses viral replication in the liver in vivo." Get all the results and reference details, order at left...
2.	Viremia 04/01/2001 - "Side-by-side comparison of beta-L-Fd4C and lamivudine administered intraperitoneally during short-term and long-term protocols demonstrated a more profound inhibition of viremia in beta-L-Fd4C-treated groups" 01/01/2000 - "Longer administration of beta-L-Fd4C induced a sustained suppression of viremia (>95% of controls) and of viral DNA synthesis within the liver" 12/01/2002 - "In vivo treatment with beta-L-Fd4C in infected ducklings and woodchucks, induced a greater suppression of viremia and intrahepatic viral DNA synthesis than with lamivudine" Get all the results and reference details, order at left...
3.	Melanoma (Melanoma, Malignant) 01/01/2003 - "This issue focuses on the following selection of drugs: 81C6; Adefovir dipivoxil, Agalsidase alfa, AGM-1470, albumin interferon alfa, alefacept, alosetron hydrochloride, anakinra, anti-CTLA-4 Mab, aprepitant, aripiprazole, atazanavir; BAY-43-9006, BBR-3438, beta-L-Fd4C, bimatoprost, bortezomib, bosentanBR96-doxorubicin; Caspofungin acetate, ciclesonide, cilengitide, cilomilast, COL-1621, COL-3, CpG-7909, cyclosporine; DCVax-Brain, dexmethylphenidate hydrochloride, dexosome vaccine (melanoma), donepezil hydrochloride, drotrecogin alfa (activated), DTI-01