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Description: a cytotoxic ent-kaurene terpenoid; isolated from the root bark of Parinari curatellifolia; structure given in first source
| 1. | Andersen, R J: 1 article (12/2001) |
| 2. | Xu, L: 1 article (12/2001) |
| 3. | Rundle, N T: 1 article (12/2001) |
| 4. | Roberge, M: 1 article (12/2001) |
| 1. | Neoplasms (Cancer)
01/05/1996
- "Two structurally novel cytotoxic ent-kaurene diterpenoids, 13-methoxy-15-oxozoapatlin and 13-hydroxy-15-oxozoapatlin, were isolated from the root bark of Parinari curatellifolia, together with the known compound, 15-oxozoapatlin, on the basis of bioactivity-guided chromatographic fractionation and found to demonstrate broad-spectrum cytotoxic activity against a panel of cultured human cancer cell lines"
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| 2. | DNA Damage
12/21/2001
- "G2 DNA damage checkpoint inhibition and antimitotic activity of 13-hydroxy-15-oxozoapatlin."
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| 2 Diseases and 2 more articles analyzed in the Research Interface, order at left... | |
| 1. | Diterpenes
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| 2. | 13-methoxy-15-oxozoapatlin
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| 3. | kaurene
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| 3 Drugs and Important Bio-Agents and 1 more articles analyzed in the Research Interface, order at left... | |
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