5-hydroxyeicosanoid dehydrogenase

NADP-dependent enzyme that catalyzes conversion of 5-HETE to 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE)

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

1.	Prostatic Neoplasms (Prostate Cancer) 06/01/2011 - "In the present study, we found that PC3 prostate cancer cells and cell lines derived from breast (MCF7) and lung (A-427) cancers contain 5-hydroxyeicosanoid dehydrogenase (5-HEDH) activity and have the ability to synthesize 5-oxo-ETE from its precursor 5S-hydroxy-6,8,11,14-eicosatetraenoic acid (5-HETE) when added as an exogenous substrate. "
2.	Neoplasms (Cancer) 06/01/2011 - "In the present study, we found that PC3 prostate cancer cells and cell lines derived from breast (MCF7) and lung (A-427) cancers contain 5-hydroxyeicosanoid dehydrogenase (5-HEDH) activity and have the ability to synthesize 5-oxo-ETE from its precursor 5S-hydroxy-6,8,11,14-eicosatetraenoic acid (5-HETE) when added as an exogenous substrate. "