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SDZ GPI 562

structure in second source; GPIIb-IIIa antagonist that prevents binding to fibrinogen from Novartis used alone or with cobra venom factor

Also Known As:

GPI 562; GPI-562; SDZ GPI-562

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Benzylamines: 10
    - SDZ GPI 562: 2
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzyl Compounds: 2
        Benzylamines: 10
        SDZ GPI 562: 2

Experts

1.	Araujo, Dalia M: 1 article (01/2003)
2.	Lapchak, Paul A: 1 article (01/2003)

Related Diseases

1.	Cerebral Infarction 10/01/1998 - "When given immediately after withdrawal of the MCA occluding suture, GPI 562 was shown to reduce cerebral infarct volumes by 70%. " 10/01/1998 - "GPI 562 exhibited a dose-dependent reduction of cerebral infarct volumes measured by triphenyltetrazolium chloride staining, as well as improvement in postischemic cerebral blood flow, measured by laser doppler. "
2.	Cerebral Hemorrhage 10/01/1998 - "GPI 562 caused a dose-dependent increase in tail vein bleeding time, but intracerebral hemorrhage (ICH) was not significantly increased at therapeutic doses; however, there was an increase in ICH at the highest doses tested. "
3.	Ischemic Stroke 01/01/2003 - "Agents such as SM-20302, TP201, ME3277, murine 7E3 F(ab')(2 )and SDZ-GPI 562 have been reported to preserve microvascular patency in different animal models of acute ischemic stroke and they may have neuroprotective properties. "

Related Drugs and Biologics

1.	triphenyltetrazolium
2.	ME 3277
3.	SM 20302

Related Therapies and Procedures

1.	Lasers (Laser)
2.	Sutures (Suture)