|1.||Umezawa, Kazuo: 8 articles (03/2015 - 11/2003)|
|2.||Kojima, Itaru: 4 articles (08/2014 - 01/2006)|
|3.||Takei, Izumi: 4 articles (08/2014 - 12/2009)|
|4.||Umezawa, K: 3 articles (03/2010 - 10/2003)|
|5.||Saito, Rie: 2 articles (08/2014 - 02/2012)|
|6.||Kawakami, M: 2 articles (03/2010 - 10/2003)|
|7.||Koyano, T: 2 articles (11/2003 - 10/2003)|
|8.||Simizu, Siro: 1 article (03/2015)|
|9.||Sasazawa, Yukiko: 1 article (03/2015)|
|10.||Sato, Natsumi: 1 article (03/2015)|
|2.||Acinar Cell Carcinoma
12/01/2004 - "We isolated conophylline from the leaves of Ervatamia microphylla as an agent that induce insulin production in rat pancreatic acinar carcinoma cells."
10/01/2003 - "Induction of insulin production in rat pancreatic acinar carcinoma cells by conophylline."
03/01/2010 - "We previously found that conophylline, an alkaloid isolated from the leaves of Ervatamia microphylla, induced beta-cell differentiation in rat pancreatic acinar carcinoma cells and in cultured fetal rat pancreatic tissue and that it also decreased the blood glucose level in streptozotocin-treated fetal rats. "
04/01/2013 - "We have also isolated from the leaves of Ervatamia microphylla conophylline, a compound that induces differentiation of beta cells from the precursor cells and was recently found to suppress islet fibrosis in diabetes model rats."
02/01/2012 - "Conophylline suppresses pancreatic stellate cells and improves islet fibrosis in Goto-Kakizaki rats."
|4.||Neurodegenerative Diseases (Neurodegenerative Disease)
|5.||Endometrial Neoplasms (Endometrial Cancer)
07/01/1999 - "When SNG-II, a highly differentiated human endometrial cancer cell line, was exposed to conophylline, the cells developed filamentous processes at concentrations which did not affect cell proliferation (0.03-0.3 microgram/ml). "
07/01/1999 - "The effect of conophylline, a new vinca alkaloid that inhibits ras expression, on tumour cell adhesion and infiltration was evaluated using a human endometrial cancer cell line. "
07/01/1999 - "Inhibition of attachment and chemotactic invasion of uterine endometrial cancer cells by a new vinca alkaloid, conophylline."
|4.||NF-kappa B (NF-kB)
|5.||Transforming Growth Factor beta (TGF-beta)
|6.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|8.||Blood Glucose (Blood Sugar)