22-1-1 antigen

expressed in cancer cells derived mainly from the uterus and ovary; distinct from the known tumor-associated antigens such as YH 206, GA 733, CA 125, and sialyl Le(x) molecules; MW 78 kDa

Also Known As:

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Anagnostopoulos, Ioannis: 1 article (05/2005)
2.	Daniel, Peter: 1 article (05/2005)
3.	Dörken, Bernd: 1 article (05/2005)
4.	Erdmann, Bettina: 1 article (05/2005)
5.	Lehmann, Insa: 1 article (05/2005)
6.	Rehm, Armin: 1 article (05/2005)
7.	Reimer, Tatiana A: 1 article (05/2005)
8.	Stein, Harald: 1 article (05/2005)

Related Diseases

1.	Neoplasms (Cancer) 05/01/1999 - "This study shows that the 22-1-1 antigen was expressed in cancer cells derived from the uterus, cervix and the ovary and may be a potential tumour marker in the management of gynaecological cancer patients." 05/01/1999 - "A preliminary study of the immunohistochemical detection of a novel tumour marker, 22-1-1 antigen, in gynaecological cancer specimens." 06/01/1998 - "Tumor-associated antigen 22-1-1 expression in the uterine cervical squamous neoplasias." 06/01/1999 - "The prognostic significance of tumor-associated antigen 22-1-1 expression in adenocarcinoma of the uterine cervix." 05/17/2005 - "This raised the question if EBAG9 is tumor-specific and mediates apoptosis itself or through O-linked glycans generated, among them the cognate 22-1-1 antigen Tn. "
2.	Adenocarcinoma 05/01/1999 - "A novel tumour associated antigen, 22-1-1, has been recently described in association with a cervical adenocarcinoma cell line. " 06/01/1999 - "The prognostic significance of tumor-associated antigen 22-1-1 expression in adenocarcinoma of the uterine cervix." 06/01/1999 - "Oncol., 6: 1099-1104, 1995) a novel monoclonal antibody, 22-1-1, generated from adenocarcinoma of the uterine cervix, and 22-1-1 antigen (Ag) was expressed in cancer cells derived mainly from the uterus and ovary. "
3.	Mucinous Cystadenocarcinoma 05/01/1999 - "This revealed positive staining for the 22-1-1 antigen in 5 out of 6 cases of cervical cancer, 3 out of 5 cases of endometrial cancers, and all 4 cases of ovarian mucinous cystadenocarcinomas. "
4.	Endometrial Neoplasms (Endometrial Cancer) 05/01/1999 - "This revealed positive staining for the 22-1-1 antigen in 5 out of 6 cases of cervical cancer, 3 out of 5 cases of endometrial cancers, and all 4 cases of ovarian mucinous cystadenocarcinomas. "
5.	Uterine Cervical Neoplasms (Cancer of the Cervix) 05/01/1999 - "This revealed positive staining for the 22-1-1 antigen in 5 out of 6 cases of cervical cancer, 3 out of 5 cases of endometrial cancers, and all 4 cases of ovarian mucinous cystadenocarcinomas. "

Related Drugs and Biologics

1.	Polysaccharides (Glycans)
2.	Monoclonal Antibodies