mocarhagin

cleaves 10 aa peptide from N terminus of P-selectin ligand receptor; cleaves the platelet von Willebrand factor receptor glycoprotein Ib alpha (GPIb alpha); GenBank AY101383

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.

Ischemia 12/01/1998 - "Control rat hearts not subjected to ischemia were perfused without blood cells for 80 min. Additional control rat hearts were perfused with 100 x 10(6) PMNs in the presence and absence of 0.2 microgram/ml mocarhagin over a 5-min perfusion followed by a 45-min observation period. " 12/01/1998 - "This study was designed to test the effects of polymorphonuclear leukocytes (PMNs) in the presence and absence of a P-selectin blocker, mocarhagin, in provoking cardiac dysfunction in isolated perfused rat hearts following ischemia and reperfusion. "

Related Drugs and Biologics

1.	P-Selectin