|1.||Peet, Daniel J: 1 article (01/2012)|
|2.||Fedele, Anthony O: 1 article (01/2012)|
|3.||Olechnowicz, Sam W Z: 1 article (01/2012)|
|4.||Deng, Caishu: 1 article (07/2009)|
|5.||Abel, Peter W: 1 article (07/2009)|
|6.||Jiang, Haihong: 1 article (07/2009)|
|7.||Qin, Jianbing: 1 article (07/2009)|
|8.||Kirui, Joseph K: 1 article (07/2009)|
|9.||Xie, Yan: 1 article (07/2009)|
|10.||Wolff, Dennis W: 1 article (07/2009)|
|1.||Schizophrenia (Dementia Praecox)
06/15/2006 - "Measurement of protein levels using Western blot demonstrated that RGS4 protein is decreased in the frontal cortex of schizophrenia cases."
06/15/2006 - "Regional alterations in RGS4 protein in schizophrenia."
01/01/2012 - "The Rgs4 gene encodes the Regulator of G-Protein Signalling 4 (RGS4) protein, an inhibitor of signalling from G-protein coupled receptors, and dysregulation of Rgs4 is linked to disease states such as schizophrenia and cardiomyopathy. "
|3.||Breast Neoplasms (Breast Cancer)
07/15/2009 - "Preventing degradation of RGS4 protein should attenuate aberrant signal inputs from multiple G(i)-coupled receptors, thereby retarding the spread of breast cancer cells and making them targets for surgery, radiation, and immune treatment."
07/15/2009 - "Interestingly, both established breast cancer cell lines and human breast cancer specimens showed that the highest levels of RGS4 protein were expressed in normal breast epithelia and that RGS4 down-regulation by proteasome degradation is an index of breast cancer invasiveness. "
07/15/2009 - "Proteasome blockade increased endogenous RGS4 protein to levels that markedly inhibit breast cancer cell migration and invasion, which was reversed by an RGS4-targeted short hairpin RNA. "
|4.||Alzheimer Disease (Alzheimer's Disease)
|1.||Proteasome Endopeptidase Complex (Proteasome)
|2.||Muscarinic M1 Receptor
|3.||G-Protein-Coupled Receptors (Receptors, G Protein Coupled)
|4.||Small Interfering RNA (siRNA)
|5.||GTP-Binding Proteins (G-Protein)