|1.||Giguère, Vincent: 7 articles (01/2010 - 11/2003)|
|2.||McDonnell, Donald P: 6 articles (10/2011 - 12/2006)|
|3.||Gao, Min: 5 articles (06/2007 - 08/2005)|
|4.||Zhao, Dan: 4 articles (10/2006 - 08/2005)|
|5.||Mertz, Janet E: 3 articles (07/2012 - 11/2002)|
|6.||Fujimoto, Jiro: 3 articles (03/2011 - 05/2007)|
|7.||Sato, Eriko: 3 articles (03/2011 - 05/2007)|
|8.||Suzuki, Takashi: 3 articles (11/2009 - 07/2004)|
|9.||Miki, Yasuhiro: 3 articles (11/2009 - 07/2004)|
|10.||Sasano, Hironobu: 3 articles (11/2009 - 07/2004)|
12/01/2015 - "Estrogen-related receptor alpha (ERRα) is one of the members of the NR superfamily and studies have linked it with a wide variety of cancers. "
12/01/2015 - "Estrogen-related receptor alpha and cancer: axis of evil."
09/15/2010 - "Accumulating evidence suggests that ERRalpha is a novel target for solid tumor therapy, conceivably through effects on the regulation of tumor cell energy metabolism associated with energy stress within solid tumor microenvironments. "
08/01/2010 - "Also, there are strong indications of the involvement of ERRalpha in cancer initiation and progression. "
04/01/2010 - "Although oestrogen-related receptor alpha (ERRalpha) is primarily thought to regulate energy homeostasis, it also serves as a prognostic marker for cancer. "
06/15/2009 - "Our findings identify AIB1 as functionally relevant cofactor for ERRalpha in breast carcinoma. "
06/15/2009 - "Estrogen-related receptor alpha expression and function is associated with the transcriptional coregulator AIB1 in breast carcinoma."
07/01/2004 - "Estrogen-related receptor alpha in human breast carcinoma as a potent prognostic factor."
11/01/2008 - "Introduction of a small interfering RNA directed to ERRalpha into the highly aggressive breast carcinoma MDA-MB-231 cell line dramatically reduced the migratory potential of these cells. "
07/01/2004 - "Results from our study suggest that ERRalpha possibly modulates the expression of ERE-containing estrogen-responsive genes, and ERRalpha immunoreactivity is a potent prognostic factor in human breast carcinoma."
02/01/2009 - "Overall, our results implicate PGC-1alpha and ERRalpha in the pathophysiology of human heart failure, and define dynamic target gene sets sharing known interrelated regulatory mechanisms capable of contributing to the mitochondrial dysfunction characteristic of this disease process."
07/01/2007 - "These results demonstrate that the nuclear receptor ERRalpha is required for the adaptive bioenergetic response to hemodynamic stressors known to cause heart failure."
07/01/2007 - "ERRalpha(-/-) mice subjected to left ventricular (LV) pressure overload developed signatures of heart failure including chamber dilatation and reduced LV fractional shortening. "
07/01/2007 - "We hypothesized that the estrogen-related receptor alpha (ERRalpha), which recruits PGC-1alpha to metabolic target genes in heart, exerts protective effects in the context of stressors known to cause heart failure. "
|4.||Endometrial Neoplasms (Endometrial Cancer)
05/01/2006 - "This study was to explore the regulatory effect of 17beta-estradiol (17beta-E(2)) on ERRalpha expression, and to elucidate the relationship between ERRalpha and ER signal pathway in endometrial carcinoma cell lines. "
01/01/2006 - "To discuss the role of ERRalpha in the endometrial carcinoma cells, this study was performed. "
08/01/2009 - "It is speculated that ERRalpha is a candidate for prognostic factors in uterine endometrial cancer, although ERRs are not directly related to growth of uterine endometrial cancer."
06/01/2007 - "Furthermore, cellular growth analysis showed that over-expression of ERRalpha induced cell growth increase of the ER negative endometrial cancer cells HEC-1A and HEC-1B (P < 0.05). "
06/01/2007 - "Plasmid of pSG-ERRalpha was transfected into endometrial cancer cell lines HEC-1A, HEC-1B, and Ishikawa. "
|5.||Breast Neoplasms (Breast Cancer)
01/01/2014 - "Novel drugs that target the estrogen-related receptor alpha: their therapeutic potential in breast cancer."
01/01/2012 - "MiR-137 targets estrogen-related receptor alpha and impairs the proliferative and migratory capacity of breast cancer cells."
05/01/2010 - "These findings provide insight into the molecular mechanisms of GPER-1/ERRalpha-mediated signaling and may be relevant to what happens in breast cancer cells escaping inhibitory control by TAM."
08/01/2009 - "Taken together, the identification and functional characterization of the ERRalpha transcriptional network implicate ERRalpha signaling as a determinant of breast cancer heterogeneity."
08/01/2009 - "Genome-wide identification of direct target genes implicates estrogen-related receptor alpha as a determinant of breast cancer heterogeneity."
|1.||ERRalpha estrogen-related receptor
|2.||Small Interfering RNA (siRNA)
|3.||Messenger RNA (mRNA)
|5.||Estrogen Receptor alpha
|7.||Proteins (Proteins, Gene)
|9.||Cytoplasmic and Nuclear Receptors (Nuclear Receptors)
|10.||Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Mammaplasty (Breast Reconstruction)