|1.||Elekes, Krisztián: 3 articles (08/2009 - 06/2006)|
|2.||Szolcsányi, János: 3 articles (08/2009 - 06/2006)|
|3.||Sándor, Katalin: 3 articles (08/2009 - 06/2006)|
|4.||Helyes, Zsuzsanna: 3 articles (08/2009 - 06/2006)|
|5.||Pintér, Erika: 3 articles (08/2009 - 06/2006)|
|6.||Doods, Henri: 2 articles (01/2015 - 08/2014)|
|7.||Just, Stefan: 2 articles (01/2015 - 08/2014)|
|8.||Pozsgai, Gábor: 2 articles (08/2009 - 01/2008)|
|9.||Kereskai, László: 2 articles (08/2009 - 01/2008)|
|10.||Bánvölgyi, Agnes: 2 articles (08/2009 - 01/2008)|
01/01/2014 - "Recent studies have shown that mice are prone to sustained pain and devoid of analgesic effect in the absence of somatostatin receptor 4 (SSTR4). "
01/05/2015 - "The somatostatin receptor 4 agonist J-2156 reduces mechanosensitivity of peripheral nerve afferents and spinal neurons in an inflammatory pain model."
01/01/2014 - "δ-opioid receptor and somatostatin receptor-4 heterodimerization: possible implications in modulation of pain associated signaling."
06/06/2006 - "Analgesic effects of the somatostatin sst4 receptor selective agonist J-2156 in acute and chronic pain models."
08/05/2014 - "This research aimed to identify possible anti-nociceptive mechanisms, showing functional links of the sst4 receptor to G-protein coupled inward rectifying potassium (GIRK) channels and reduction of voltage stimulated calcium influx within the pain processing pathway. "
01/14/2008 - "These results suggest that stable, somatostatin sst(4) receptor-selective agonists could be potential candidates for the development of a completely novel group of anti-inflammatory drugs for the treatment of airway inflammation and hyperresponsiveness."
01/14/2008 - "The aim of this study was to examine the effects of TT-232, a heptapeptide sst(4)/sst(1) receptor agonist and J-2156, a high affinity sst(4) receptor-selective peptidomimetic agonist in airway inflammation models. "
|3.||Alzheimer Disease (Alzheimer's Disease)
03/01/2011 - "These results suggest sst4 receptor agonists may provide a viable therapy in the treatment of Alzheimer's disease and other forms of cognitive impairment."
03/01/2011 - "The second goal of this study was to evaluate the effect of chronic NNC 26-9100 administration (i.p.) on learning and memory, brain Aβ(x-42) levels, and protein expression of sst4 receptor and amyloid precursor protein (APP) in the senescence-accelerated mouse p8 (SAMP8) model of Alzheimer's disease. "
09/01/2002 - "L-803087 (5 nmol), a selective sst4 receptor agonist, doubled seizure activity in wild-type mice on average. "
04/02/2008 - "Using pentylenetetrazole as a chemoconvulsant, SST(2), SST(3), and SST(4) receptor knock-out mice all had shorter latencies to different seizure stages and increased seizure severity when compared with wild-type mice. "
|5.||Ganglion Cysts (Ganglion)
10/01/2006 - "sst(1), sst(2A), and sst(4) receptor immunoreactivities were observed in processes of the inner plexiform layer (IPL), rod bipolar, and in ganglion cells and processes, respectively, in WT and SRIF (-/-) mice. "
10/01/2006 - "Monoclonal antibodies [SRIF, protein kinase C (rod bipolar cells marker), microtubule associated protein 1A (ganglion cell marker)] and polyclonal antibodies (anti-sst(1), sst(2A), sst(4) receptor) were applied to 10-14 microm sections of retinas fixed in paraformaldehyde. "
|1.||2S)- 4- amino- N- (1'- carbamoyl- 2'- phenylethyl)- 2- (4''- methyl- 1''- naphthalenesulfonylamino)butanamide (1'S
|2.||Amyloid (Amyloid Fibrils)
|5.||Somatostatin (Somatotropin Release-Inhibiting Factor)
|8.||GTP-Binding Proteins (G-Protein)
|9.||Opioid Receptors (Opioid Receptor)
|10.||Protein Kinase C