|1.||Fukushima, Shoji: 6 articles (10/2015 - 11/2011)|
|2.||Hagiwara, Akihiro: 5 articles (10/2015 - 11/2011)|
|3.||Imai, Norio: 5 articles (10/2015 - 11/2011)|
|4.||Nagano, Kasuke: 5 articles (10/2015 - 11/2011)|
|5.||Doi, Yuko: 3 articles (10/2015 - 11/2011)|
|6.||Furukawa, Fumio: 3 articles (10/2015 - 11/2011)|
|7.||Kawabe, Mayumi: 3 articles (10/2015 - 11/2011)|
|8.||Tamano, Seiko: 2 articles (10/2015 - 11/2011)|
|9.||Suguro, Mayuko: 2 articles (10/2015 - 12/2013)|
|10.||Wei, Min: 2 articles (01/2015 - 12/2013)|
|1.||Body Weight (Weight, Body)
06/01/2010 - "Seven GLP-compliant studies following widely accepted protocols have focused specifically on developmental and reproductive toxicity (DART) in rats and rabbits exposed to ETBE by gavage with doses up to 1,000 mg/kg body weight/day, the limit specified in standardized test guidelines. "
12/01/1995 - "In contrast, no ETBE exposed animals died during the study and no changes in body weight gain were observed. "
01/01/2015 - "F344 rats were administered ETBE at doses of 0, and 1,000 mg/kg body weight twice a day by gavage for 3, 10, 17 and 28 days. "
07/01/2014 - "ETBE was administered at dose levels of 0, 5, 25, 100 and 400 mg/kg/body weight (b.w.)/day by gavage. "
10/01/2011 - "ETBE-exposure did not affect the weight of the spleen or body weight, while it transiently increased the number of RBC and the Hb concentration. "
11/01/2015 - "These results support the hypothesis that TBA mediates the noncancer kidney and liver effects following ETBE administration; however, additional factors besides internal dose are necessary to explain the induction of liver and kidney tumors. "
10/01/2015 - "Thus, these results imply that ETBE has hepatic and renal tumor-promoting activities that affect EHEN-induced carcinogenesis in male rats, and the no-observed-effect level is 500 mg/kg/day under the present experimental conditions. "
10/01/2015 - "No significant differences in incidences and average numbers of renal tubule neoplasms were found in rats administered 100‒1,000 mg/kg/day ETBE. "
11/18/2011 - "Thus, the current results indicate that ETBE has tumor promoting potential for the thyroid and forestomach at dose levels of 300mg/kg/day and more, and for the colon, liver, kidney and urinary bladder at 1000mg/kg/day, under the present experimental conditions."
01/01/2013 - "Previous reports have indicated that exposure to ETBE or methyl tertiary-butyl ether resulted in liver and kidney tumors in rats and/or mice. "
11/01/2015 - "The results demonstrate that noncancer kidney effects, including kidney weight changes, urothelial hyperplasia, and chronic progressive nephropathy (CPN), yielded consistent dose-response relationships across routes of exposure and across ETBE and TBA studies using TBA blood concentration as the dose metric. "
10/01/2015 - "However, the average numbers of atypical tubule hyperplasias, considered to be preneoplastic lesions, were significantly increased in rats given ETBE at 1,000 mg/kg/day, but not in rats given 500 mg/kg/day or lower doses. "
10/01/2015 - "Incidences of hepatocellular adenomas, and those of combined hepatocellular adenomas and carcinomas were significantly elevated in rats given 1,000 mg/kg/day ETBE, but not 100‒500 mg/kg/day ETBE, and there was a significant increase in the average numbers of lesions. "
12/01/2013 - "No statistically significant differences in incidences of preneoplastic lesions, papillomas, and carcinomas of the urinary bladder were evident in rats treated with 100-1000 mg/kg/day ETBE as compared with control values. "
|1.||ethyl tert-butyl ether (ETBE)
|2.||tert-Butyl Alcohol (tert-Butanol)
|3.||methyl tert-butyl ether (MTBE)
|4.||Gasoline (Diesel Fuel)
|9.||Messenger RNA (mRNA)
|10.||Immunoglobulin M (IgM)
|2.||Cesarean Section (Caesarean Section)