neoisoliquiritin

inhibits angiogenesis; isolated from licorice root; isoliquiritin is the (E)-isomer; structure in first source; isoliquiritin is also available

Also Known As:

4-((1E)-3-(2,4-dihydroxyphenyl)-3-oxo-1-propen-1-yl)phenyl beta-D-glucopyranoside; isoliquiritin; neoisoliquiritin, (E)-isomer; 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-(beta-D-glucopyranosyloxy)phenyl)-

Networked: 25 relevant articles (4 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	He, Ming-Fang: 2 articles (03/2021 - 05/2020)
2.	Li, Chong-Yong: 2 articles (03/2021 - 05/2020)
3.	Chen, Hongbing: 1 article (01/2022)
4.	Gui, Zhen: 1 article (01/2022)
5.	Jia, Zhanjun: 1 article (01/2022)
6.	Li, Xiaonan: 1 article (01/2022)
7.	Long, Guangfeng: 1 article (01/2022)
8.	Pei, Zhiyin: 1 article (01/2022)
9.	Wu, Meng: 1 article (01/2022)
10.	Xia, Weiwei: 1 article (01/2022)

Related Diseases

1.	Inflammation (Inflammations) 07/31/2023 - "Isoliquiritin could reduce intestinal inflammation and mucosal damage of TNBS-induced colitis in rats with a certain anti-UC effect. " 01/01/2022 - "Isoliquiritin Ameliorates Cisplatin-Induced Renal Proximal Tubular Cell Injury by Antagonizing Apoptosis, Oxidative Stress and Inflammation." 05/01/2021 - "Neoisoliquiritin (NEO) belongs to the class of licorice (Glycyrrhiza) flavonoids, which have a variety of biological activities including anti-depressant, anti-tumor-promoting, and anti-inflammation properties. "
2.	Pain (Aches) 09/16/2013 - "Increasing the amount of RP attenuated the inhibitory effect of GA via competing being consumed by intestinal bacteria (or β-glucosidase) to reduce the conversion amount of glycyrrhizin to GA and subsequently to afford significantly higher bioavailability and longer efficacy of PF, glycyrrhizin, albiflorin, oxypaeoniflorin, isoliquiritin, and ononin, leading to better spasmolysis and emergency pain relief."
3.	Hypersensitivity (Allergy) 08/15/2020 - "Collectively, these findings demonstrate, for the first time, the therapeutic efficacy of isoliquiritin on neuropathic hypersensitivity, and this effect is dependent on the spinal serotonergic system and 5-HT1A receptors."
4.	Ulcerative Colitis 07/31/2023 - "Isoliquiritin Ameliorates Ulcerative Colitis in Rats through Caspase 3/HMGB1/TLR4 Dependent Signaling Pathway." 07/31/2023 - "The inflammatory [trinitro-benzene-sulfonic acid-TNBS-induced ulcerative colitis (UC)] model was established to ascertain the effect of isoliquiritin on the caspase-3/HMGB1/TLR4 pathway in rats. "
5.	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/01/2017 - "Paeoniflorin, albiflorin, baicalin, isoliquiritin and liquiritin have been reported to relieve depression in vivo or in clinical trials, which might be the active ingredients for FAEW against PTSD."

Related Drugs and Biologics

1.	Glycyrrhizic Acid (Glycyrrhizin)
2.	albiflorin
3.	calycosin-7-O-beta-D-glucoside
4.	Caspase 3 (Caspase-3)
5.	HMGB1 Protein (HMG1)
6.	Glucosidases
7.	Cisplatin (Platino)
8.	oxypaeoniflora
9.	liquiritin
10.	Therapeutic Uses

Related Therapies and Procedures

1.	Therapeutics