HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

1-(2-trifluoromethylphenyl)imidazole

an inhibitor of neuronal nitric oxide synthase in mouse

Also Known As:

1-TRIM

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - 1-(2-trifluoromethylphenyl)imidazole: 4

Experts

1.	Fazan, Rubens: 1 article (03/2006)
2.	Joaquim, Luis F: 1 article (03/2006)
3.	Justo, Soraia V S: 1 article (03/2006)
4.	Salgado, Helio C: 1 article (03/2006)
5.	Salgado, Maria Cristina O: 1 article (03/2006)
6.	Bakhle, Y S: 1 article (07/2000)
7.	Beddy, P: 1 article (07/2000)
8.	Bell, C: 1 article (07/2000)
9.	Campbell, V A: 1 article (07/2000)
10.	Foley, A: 1 article (07/2000)

Related Diseases

1.	Inflammation (Inflammations) 07/28/2000 - "The present study measured tracheal inflammation to resiniferatoxin (1.0 microgram/kg i.v.), a capsaicin analogue, which lacks the hypotensive action of capsaicin itself, alone or after the neuronal nitric oxide synthase inhibitor 1-(2-trifluoromethylphenyl)imidazole (TRIM) (50 mg/kg i.p.). "
2.	Neurogenic Inflammation 05/11/1998 - "The effects of a neuronal nitric oxide synthase (nNOS) inhibitor, 1-(2-trifluoromethylphenyl)imidazole (TRIM) on rat sensory saphenous nerve-induced neurogenic inflammation were investigated. "
3.	Brain Ischemia (Cerebral Ischemia) 03/01/1998 - "The novel neuronal nitric oxide synthase inhibitors, 1-(2-trifluoromethylphenyl)imidazole (TRIM) and 7-nitro indazole (7-NI), were used to investigate the role of nitric oxide in a model of transient focal cerebral ischemia in vivo. "
4.	Aortic Coarctation 03/01/2006 - "Increase in pressure was induced either by administration of the nonselective NOS inhibitor N(G)-nitro-L-arginine methyl ester (L-NAME) or aortic coarctation (COA) with or without treatment with the COX inhibitor indomethacin (INDO) or the selective neuronal NOS inhibitor 1-(2-trifluoromethylphenyl)imidazole (TRIM). "

Related Drugs and Biologics

1.	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)
2.	Capsaicin (Zostrix)
3.	resiniferatoxin
4.	NG-Nitroarginine Methyl Ester (L-NAME)
5.	Nitric Oxide (Nitrogen Monoxide)
6.	Indomethacin (Indometacin)
7.	Indazoles
8.	Coenzyme A (CoA)