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SDZ 281 977

a derivative of lavendustin A

Also Known As:

5-(2-(2,5-dimethoxyphenyl)ethyl)-2-hydroxybenzoic acid methyl ester; SDZ 281-977

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzoates: 426
        SDZ 281 977: 1
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Benzoates: 426
      - SDZ 281 977: 1

Related Diseases

1.

Neoplasms (Cancer)

01/26/1996 - "Studies in mice indicated that SDZ 281-977 was neither immunosuppressive nor hematosuppressive at doses effectively inhibiting tumor growth. "
01/26/1996 - "SDZ 281-977 may be a candidate drug for the treatment of selected cancers, including those expressing the multidrug resistance phenotype."
01/26/1996 - "The therapeutic potential of SDZ 281-977 is enhanced by the fact that it is not subject to multidrug resistance, because tumor cells expressing the multidrug resistance phenotype were as sensitive to SDZ 281-977 as their nonresistant counterparts. "
01/26/1996 - "Tumors from these cells were induced in nude mice and were shown to respond to orally or intravenously administered SDZ 281-977. "