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thanatin

insect defense protein of 21 residues isolated from Podisus maculiventris; amino acid sequence in first source

Also Known As:

S-thanatin

Networked: 18 relevant articles (4 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Pore Forming Cytotoxic Proteins
      - Antimicrobial Cationic Peptides: 414
        thanatin: 18
- Peptides: 82426
  - Antimicrobial Peptides: 3727
    - Antimicrobial Cationic Peptides: 414
      - thanatin: 18
  - Antimicrobial Cationic Peptides: 414
    - thanatin: 18

Experts

1.	Wu, Guoqiu: 8 articles (01/2015 - 03/2010)
2.	Shen, Zilong: 7 articles (07/2013 - 03/2010)
3.	Hou, Zheng: 4 articles (01/2019 - 01/2011)
4.	Luo, Xiaoxing: 4 articles (01/2019 - 01/2011)
5.	Xue, Xiaoyan: 4 articles (01/2019 - 01/2011)
6.	Zhou, Ying: 4 articles (01/2019 - 01/2011)
7.	Fan, Xiaobo: 4 articles (01/2015 - 03/2010)
8.	Xi, Tao: 4 articles (07/2013 - 03/2010)
9.	Wu, Pengpeng: 3 articles (01/2015 - 07/2012)
10.	Li, Linxian: 3 articles (04/2011 - 03/2010)

Related Diseases

1.	Sepsis (Septicemia) 01/01/2015 - "S-thanatin functionalized liposome potentially targeting on Klebsiella pneumoniae and its application in sepsis mouse model." 04/01/2011 - "S-thanatin in vitro prevents colistin resistance and improves its efficacy in an animal model of Pseudomonas aeruginosa sepsis." 07/01/2010 - "We investigated the efficacy of the peptide s-thanatin alone and in combination with tigecycline in an animal model of sepsis induced by cecal ligation and puncture. "
2.	Hemolysis 01/15/2011 - "A-thanatin is highly effective against ESBL-EC in vitro, with MIC values ≤4 μg/mL. It has been confirmed that A-thanatin has little hemolysis and relative high stability in plasma. " 09/01/2010 - "In hemolysis assay, S-thanatin exhibited low hemolytic activity and bacteria selectivity. "
3.	Septic Shock (Toxic Shock Syndrome) 03/01/2010 - "The results showed that s-thanatin not only completely bound to the LPS (median effective concentration of 17.5microg/mL) but also improved the survival and reduced the number of inoculated bacteria in a mouse model of septic shock. " 03/01/2010 - "Interaction of antimicrobial peptide s-thanatin with lipopolysaccharide in vitro and in an experimental mouse model of septic shock caused by a multidrug-resistant clinical isolate of Escherichia coli."
4.	Shock 02/01/2011 - "Protective effects of antimicrobial peptide S-thanatin against endotoxic shock in mice introduced by LPS."
5.	Peritonitis 07/01/2010 - "S-thanatin enhances the efficacy of tigecycline in an experimental rat model of polymicrobial peritonitis." 07/01/2010 - "S-thanatin may have potential therapeutic usefulness alone and when associated to tigecycline in polymicrobial peritonitis."

Related Drugs and Biologics

1.	Antimicrobial Peptides
2.	Peptides (Polypeptides)
3.	Tigecycline (Tygacil)
4.	thanatin
5.	Liposomes (Liposome)
6.	Lipopolysaccharides
7.	Colistin (Coly-Mycin)
8.	Anti-Bacterial Agents (Antibiotics)
9.	Amino Acids
10.	Adenosine Monophosphate (AMP)

Related Therapies and Procedures

1.	Punctures
2.	Ligation
3.	Therapeutics