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4-hydroxyphenylacetaldehyde
the major product of L-tyrosine oxidation by activated human phagocytes
Also Known As:
p-hydroxyphenylacetaldehyde; pOH-Ph-CH2CHO
Networked:
4
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Aldehydes: 2153
Acetaldehyde: 1345
4-hydroxyphenylacetaldehyde: 4
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Benzene Derivatives: 17
Phenols: 677
Phenol: 2172
4-hydroxyphenylacetaldehyde: 4
Related Diseases
1.
Inflammation (Inflammations)
01/01/1999 - "
Our previous studies indicated that p-hydroxyphenylacetaldehyde (pHA), the major product of L-tyrosine oxidation by the myeloperoxidase/hydrogen peroxide/chloride system of phagocytes, covalently modifies the epsilon-amino group of lysine residues at sites of inflammation.
"
2.
Dehydration (Water Stress)
12/05/1990 - "
This indicates that the conversion of p-hydroxyphenylacetaldehyde oxime into p-hydroxyphenylacetonitrile proceeds by a simple dehydration reaction.
"
05/01/1991 - "
Due to the complex kinetics of the microsomal enzyme system, these requirements may not appertain to the oxime-metabolizing enzyme, which may convert p-hydroxyphenylacetaldehyde oxime to p-hydroxyacetonitrile by a simple dehydration.
"
3.
Neoplasms (Cancer)
05/17/1968 - "
The major deaminated metabolite of tyramine-H(3) in the incubation mixtures with the tumors or with the cultured cells is p-hydroxyphenylacetaldehyde.
"
Related Drugs and Biologics
1.
Tyrosine (L-Tyrosine)
2.
Peroxidase (Myeloperoxidase)
3.
Lysine (L-Lysine)
4.
Hydrogen Peroxide (Hydroperoxide)
5.
Chlorides
6.
Oximes
7.
Enzymes
8.
glycolonitrile