buforin II

12/07/2020 - "The efficacy of combination treatment with 2-DG and buforin IIb in prostate cancer remains unknown. "
12/07/2020 - "Collectively, the current study demonstrates that dual targeting of glycolysis and mitochondria by 2-DG and buforin IIb may be an effective anticancer strategy for the treatment of some advanced prostate cancer."
12/07/2020 - "These results suggest that 2-DG sensitizes prostate cancer DU145 cells to buforin IIb. "
10/01/2019 - "In conclusion, our results indicated that buforin IIb induced PC-3 and Du-145 cell apoptosis and could be considered as a potential drug for prostate cancer."
10/01/2019 - "However, the molecular mechanism of buforin IIb on prostate cancer cell has still not been determined. "

11/18/2008 - "Overall, these results suggest that buforin IIb constitutes a novel therapeutic agent for the treatment of cancers."
12/07/2020 - "Combining 2-DG with buforin IIb had a synergistic toxic effect on DU145 cells and mouse xenograft tumors. "
10/01/2019 - "In addition, buforin IIb increased the expression of tumor suppressor p53 and its target genes - p21, fas, noxa and puma. "
06/01/2019 - "Furthermore, 50 nmol buforin IIb injection suppressed HepG2 cell subcutaneous tumor growth in the nude mouse model. "
06/01/2019 - "A tumor growth model was constructed using nude mice, and buforin IIb treatment was administered. "

04/01/2009 - "In an experimental model, buforin II and rifampin might have a potential role in the treatment of severe infections due to A. "
12/01/2000 - "A rat model was used to investigate the efficacies of two peptides, ranalexin and buforin II, in the prevention of vascular prosthetic graft infections. "
11/01/2000 - "A rat model was used to investigate the efficacy of two polycationic peptides, ranalexin and buforin II, in the prevention of vascular prosthetic graft infection due to methicillin-resistant Staphylococcus epidermidis with intermediate resistance to glycopeptides. "
01/01/2022 - "In order to obtain a viable administration route to counteract superficial skin infections (impetigo, abscesses, furuncles, and cellulitis), a topical formulation based on Magnetite-Buforin-II-silver nanobioconjugates as active antibacterial agents was designed by their dispersion in O/W concentrated emulsions. "

04/01/2009 - "Therapeutic efficacy of buforin II and rifampin in a rat model of Acinetobacter baumannii sepsis."
04/01/2009 - "To investigate the efficacy of buforin II and rifampin in an experimental rat model of Acinetobacter baumannii sepsis. "
07/01/2002 - "The therapeutic efficacies of buforin II, indolicidin, and KFFKFFKFF were investigated in three rat models of septic shock: (i) rats injected intraperitoneally with 10 microg of Escherichia coli O111:B4 lipopolysaccharide, (ii) rats given an intraperitoneal injection of 2 x 10(10) CFU of Escherichia coli ATCC 25922, and (iii) rats in which intra-abdominal sepsis was induced via cecal ligation and single puncture. "

06/01/2019 - "The aim of the present study was to investigate the effects of buforin IIb on the progression of liver cancer. "
06/01/2019 - "Treatment with buforin IIb also inhibited the migration of liver cancer cells in vitro. "
06/01/2019 - "The human liver cancer cell line HepG2 was treated with purified buforin IIb and the cell activity was determined by MTT, colony formation and transwell assays. "
06/01/2019 - "Buforin IIb induced cell cycle arrest in liver cancer."
06/01/2019 - "The inhibitory effect of buforin IIb on different types of cancer, although not liver cancer, has been demonstrated previously. "