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1,12-diaziridinyl-4,9-diazadodecane

structure in first source

Also Known As:

NSC 667005; NSC-667005

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azirines
    - Aziridines: 14
      - 1,12-diaziridinyl-4,9-diazadodecane: 2
Organic Chemicals: 133
- Amines: 4871
  - Polyamines: 3918
    - Spermine: 1076
      - 1,12-diaziridinyl-4,9-diazadodecane: 2
  - Biogenic Amines: 992
    - Biogenic Polyamines: 11
      - Putrescine: 919
        Spermidine: 1153
        Spermine: 1076
        1,12-diaziridinyl-4,9-diazadodecane: 2

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 11/01/1998 - "Tumor-targeted apoptosis by a novel spermine analogue, 1,12-diaziridinyl-4,9-diazadodecane, results in therapeutic efficacy and enhanced radiosensitivity of human prostate cancer."
2.	Neoplasms (Cancer) 11/01/1998 - "Tumor-targeted apoptosis by a novel spermine analogue, 1,12-diaziridinyl-4,9-diazadodecane, results in therapeutic efficacy and enhanced radiosensitivity of human prostate cancer."
3.	Leukemia 01/05/1996 - "A significant increase in life span of female CD2F1 mice bearing L1210 murine leukemia was observed after intravenous administration of 1,12-diaziridinyl-4,9-diazadodecane in doses of less than 2.7 mg/kg, given on days 1, 5, and 9 of treatment."

Related Drugs and Biologics

1.	Spermine

Related Therapies and Procedures

1.	Intravenous Administration