gamma-fluorofolic acid

structure in first source

Also Known As:

L-t-gamma-FFA; L-threo-gamma-fluorofolic acid

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Leukemia 10/25/1996 - "Folic acid, DL-e,t-gamma-fluorofolic acid, LV, and DL-e,t-gamma-FLV each potentiated the growth inhibitory effect of 5-fluoro-2'-deoxyuridine on CCRF-CEM human leukemia cells; higher concentrations of fluorinated analogs again were required. "
2.	Hepatocellular Carcinoma (Hepatoma) 10/25/1996 - "Compared to folic acid, DL-e,t-gamma-fluorofolic acid, a compound that is a poor substrate for polyglutamylation, was approximately 25-fold less potent in promoting growth of folate-depleted H35 rat hepatoma cells. "