|1.||Symons, Marc: 4 articles (01/2015 - 04/2003)|
|2.||Di Paolo, Gilbert: 3 articles (10/2012 - 07/2008)|
|3.||Volpicelli-Daley, Laura: 2 articles (11/2013 - 12/2012)|
|4.||Soda, Keita: 2 articles (07/2013 - 12/2012)|
|5.||Ishibe, Shuta: 2 articles (07/2013 - 12/2012)|
|6.||De Camilli, Pietro: 2 articles (12/2012 - 07/2008)|
|7.||Giovedi, Silvia: 2 articles (12/2012 - 07/2008)|
|8.||Berman, Diego E: 2 articles (10/2012 - 07/2012)|
|9.||Arancio, Ottavio: 2 articles (10/2012 - 07/2008)|
|10.||Antonarakis, Stylianos E: 2 articles (07/2012 - 07/2008)|
|1.||Alzheimer Disease (Alzheimer's Disease)
10/31/2012 - "Reduction of synaptojanin 1 ameliorates synaptic and behavioral impairments in a mouse model of Alzheimer's disease."
11/01/2013 - "Recent studies link synaptojanin 1 (synj1), the main phosphoinositol (4,5)-biphosphate phosphatase (PI(4,5)P2-degrading enzyme) in the brain and synapses, to Alzheimer disease. "
01/01/2014 - "Synaptophysin and synaptojanin-1 in Down syndrome are differentially affected by Alzheimer's disease."
11/15/2004 - "This study also identifies synaptojanin 2 as a novel potential target for therapeutic intervention in malignant tumors."
11/01/2012 - "Synaptojanin 2 (SYNJ2) is a phosphatidylinositol (PI) phosphatase that controls two distinct functions, clathrin-mediated endocytosis and tumor cell invadopodia formation and invasion. "
|3.||Down Syndrome (Down's Syndrome)
06/01/2009 - "Synaptojanin-1 plays a key role in astrogliogenesis: possible relevance for Down's syndrome."
07/08/2008 - "Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome."
03/01/2002 - "We investigated the expression of synaptojanin, which has been mapped on 21q22.2 on human chromosome, in the cerebral cortex of patients with Down syndrome (DS), using immunohistochemistry and immunoblotting. "
03/01/2002 - "Excessive expression of synaptojanin in brains with Down syndrome."
07/15/2012 - "Trisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes."
|4.||Oculocerebrorenal Syndrome (Lowe Syndrome)
10/08/2004 - "The catalytic properties of the type II phosphoinositide 5-phosphatases of Lowe's oculocerebrorenal syndrome, INPP5B, Synaptojanin1, Synaptojanin2 and SKIP were analysed with respect to their substrate specificity and enzymological properties. "
02/01/2013 - "The four mammalian phosphatidylinositol 4-kinases, together with the PI(4,5)P(2) depleting 5-phosphatases of the oculocerebrorenal syndrome of Lowe and synaptojanin families, modulate neuronal pools of PI4P lipid and regulate intracellular membrane trafficking in the endocytic and secretory pathways. "
12/08/1998 - "Five mammalian enzymes and multiple splice variants are known: INPP5P or inositol polyphosphate 5-phosphatase II, OCRL (a Golgi protein implicated in the Lowe oculocerebrorenal syndrome), synaptojanin (a protein involved in the recycling of synaptic vesicles), SHIP 1 and SHIP 2 (or SH2-containing inositol 5-phosphatases). "
02/15/2015 - "Hyperosmotic shock promotes calcineurin binding to and dephosphorylation of the PI(4,5)P2 phosphatase synaptojanin/Inp53/Sjl3 and causes dramatic calcineurin-dependent reorganization of PI(4,5)P2-enriched membrane domains. "
11/01/2015 - "From the proteins that were differentially regulated between the delayed- and the immediate-shock groups at 4 h, 48 proteins, most prominently representing endocytosis, (amphiphysin, dynamin, and synaptojanin1), glutamate signaling (glutamate [NMDA] receptor subunit epsilon-1, disks large homolog 3), and neurotransmitter metabolism (excitatory amino acid transporter 1, excitatory amino acid transporter 2, sodium- and chloride-dependent GABA transporter 3) were regulated in both protocols, but in opposite directions, pointing toward an interaction of learning and stress. "
|5.||GABA Plasma Membrane Transport Proteins
|6.||Small Interfering RNA (siRNA)
|7.||Excitatory Amino Acid Transporter 2
|8.||Excitatory Amino Acid Transporter 1 (Glutamate Aspartate Transporter 1)
|10.||Glutamic Acid (Glutamate)