|1.||Pierre, Jean-Louis: 2 articles (12/2006 - 07/2006)|
|2.||Lescoat, Gérard: 2 articles (12/2006 - 07/2006)|
|3.||Pasdeloup, Nicole: 2 articles (12/2006 - 07/2006)|
|4.||Brissot, Pierre: 2 articles (12/2006 - 07/2006)|
|5.||Gaboriau, François: 2 articles (12/2006 - 07/2006)|
|6.||Laupen-Chassay, Cindy: 1 article (12/2006)|
|7.||Havouis, René: 1 article (07/2006)|
|8.||Nick, Hanspeter: 1 article (07/2006)|
|9.||Chantrel-Groussard, Karine: 1 article (07/2006)|
|10.||Buss, Joan L: 1 article (06/2003)|
|1.||Hepatocellular Carcinoma (Hepatoma)
05/01/2000 - "Antiproliferative and apoptotic effects of O-Trensox, a new synthetic iron chelator, on differentiated human hepatoma cell lines."
07/17/2006 - "Moreover, the two chelators exhibit some cytotoxic effect in the two culture models; ICL670A was more cytotoxic than O-trensox and higher concentrations of the two chelators were necessary to induce a cytotoxicity in primary cultures versus hepatoma cells. "
07/17/2006 - "By comparing the antiproliferative effect of the iron chelators ICL670A and O-trensox in the human hepatoma cell line HUH7 and human hepatocyte cultures, we have shown that ICL670A decreased cell viability, inhibited DNA replication and induced DNA fragmentation more efficiently than O-trensox. "
12/01/2006 - "The antiproliferative effects of the iron chelator O-trensox and the ornithine-decarboxylase (ODC) inhibitor alpha-difluoromethylornithine (DFMO) were characterized in the rat hepatoma cell line FAO, the rat liver epithelial cell line (RLEC) and the primary rat hepatocyte cultures stimulated by EGF. "
06/01/2003 - "The anti-tumor activity of the PIH analogs and other chelators such as tachpyridine, O-trensox and the desferrithiocin analogs have been well characterized in vitro. "
06/01/2003 - "Examples of iron chelators that have shown promising anti-tumor activity (in various stages of development) include heterocyclic carboxaldehyde thiosemicarbazones, analogs of pyridoxal isonicotinoyl hydrazone, tachpyridine, O-trensox, desferrithiocin, and other natural and synthetic chelators. "
|4.||Hypochromic Anemia (Chlorosis)
|6.||Ornithine Decarboxylase (Decarboxylase, Ornithine)
|7.||Epidermal Growth Factor (EGF)