|1.||Fujiyama, Yoshihide: 3 articles (01/2003 - 04/2002)|
|2.||Bamba, Tadao: 3 articles (01/2003 - 04/2002)|
|3.||Makino, Jin: 2 articles (08/2002 - 04/2002)|
|4.||Shikama, Hiroshi: 2 articles (08/2002 - 04/2002)|
|5.||Hata, Kazunori: 2 articles (08/2002 - 04/2002)|
|6.||Yotsuya, Shuichi: 2 articles (08/2002 - 04/2002)|
|7.||Andoh, Akira: 2 articles (08/2002 - 04/2002)|
|8.||Yamabayashi, Cristiane: 1 article (09/2009)|
|9.||Suzuki, Eiichi: 1 article (09/2009)|
|10.||Moriyama, Hiroshi: 1 article (09/2009)|
08/01/2002 - "Inhibitory effects of the new anti-inflammatory agent, IS-741, on spontaneous colitis in HLA-B27/beta2-microglobulin transgenic rats."
04/01/2002 - "In conclusion, IS-741 suppressed DSS-induced experimental colitis in rats. "
10/01/2001 - "We examined the therapeutic effects of the inflammatory cell infiltration inhibitor IS-741 (N-(2-((ethylsulfonyl)amino)-5-(trifluoromethyl)-3-pyridinyl)-cyclohexanecarboxamide monosodium salt monohydrate) on a rat colitis model. "
08/01/2002 - "In the present study, the authors examined the efficacy of IS-741 against spontaneous colitis in HLA-B27 rats. "
04/01/2002 - "We examined the efficacy of IS-741 in a dextran sulfate sodium (DSS)-induced colitis model. "
01/01/1999 - "Furthermore, IS-741 at identical plasma concentrations equally improved the survival rates in animals of various species with severe acute pancreatitis. "
11/01/2004 - "IS-741, a new synthetic anti-inflammatory agent, has been studied on various models of experimental pancreatitis. "
01/01/2003 - "The severity of acute pancreatitis was alleviated in rats treated with IS-741 (IS group). "
01/01/2003 - "Tissue destruction arising from neutrophil infiltration of the pancreas and other organs in acute pancreatitis is supposed to be suppressed by IS-741. "
02/01/1999 - "The effect of IS-741 (N-[(2-ethylsulfonylamino)-5-trifluoromethyl-3-pyridyl] cyclohexanecarboxamide monohydrate) on a model for pancreatitis has been previously reported. "
01/01/2003 - "These results indicate that the oral administration of IS-741 inhibits neutrophil infiltration into inflamed lesions, and is effective for attenuating rat TNBS ileitis. "
01/01/2003 - "In this study, we used rat trinitrobenzene sulfonic acid (TNBS) ileitis as a Crohn's disease model, and investigated the effects of oral IS-741 (which inhibits the expression of Mac-1, a cell adhesion molecule) on leukocyte-endothelial interactions. "
|4.||Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/01/2002 - "This study aimed to analyze the therapeutic effects of the carboxamide derivative IS-741 on spontaneous chronic pancreatitis (CP) in the WBN/Kob rat. "
01/01/2002 - "Effect of carboxamide derivative IS-741 on rat spontaneous chronic pancreatitis."
04/01/2007 - "IS-741 attenuates local migration of monocytes and subsequent pancreatic fibrosis in experimental chronic pancreatitis induced by dibutyltin dichloride in rats."
|3.||HLA-B27 Antigen (HLA B27 Antigen)
|5.||Phospholipases A2 (Phospholipase A2)
|6.||Proliferating Cell Nuclear Antigen (PCNA)
|7.||Interleukin-8 (Interleukin 8)
|10.||DNA (Deoxyribonucleic Acid)