|1.||Cronstein, Bruce N: 4 articles (03/2015 - 08/2006)|
|2.||Martín, Mairena: 2 articles (08/2015 - 06/2008)|
|3.||Wilder, Tuere: 2 articles (03/2015 - 06/2008)|
|4.||Perez-Aso, Miguel: 2 articles (03/2015 - 10/2012)|
|5.||Chiriboga, Luis: 2 articles (10/2012 - 06/2008)|
|6.||Chen, Jiang-Fan: 2 articles (04/2010 - 08/2006)|
|7.||Koos, Brian J: 2 articles (03/2009 - 05/2005)|
|8.||Chan, Edwin S L: 2 articles (06/2008 - 08/2006)|
|9.||Winn, H Richard: 2 articles (05/2003 - 01/2002)|
|10.||Vargas-Morales, Juan M: 1 article (08/2015)|
04/01/2012 - "We are led to the conclusion that although ZM241385 had no influence on the progression of amygdala-kindled seizures, it had potent anti-convulsant profile and little adverse effects at the dosage of 0.001-0.1 nmol/L, suggesting that the agent is effective against the amygdala-kindled seizures."
04/01/2012 - "In contrast to the results in fully amygdala-kindled rats, ZM241385 (0.001-0.1 nmol/L) had minimal or no effects on the progression of amygdala-kindled seizures. "
04/01/2012 - "The dosages of 0.0001 and 1 nmol/L of ZM241385 did not exert any effect on all seizure parameters. "
04/01/2012 - "The results showed that, in fully amygdala-kindled rats, ZM241385 (0.001-0.1 nmol/L) decreased afterdischage duration (ADD), motor seizure duration (MSD), stage 5 duration (S5D) and seizure duration (SD), but only the effect on ADD was dose-dependent. "
08/01/2015 - "In contrast, a significant decrease in A2A receptor density was detected, using [(3) H]ZM241385 as radioligand, 48 h after hyperthermia-evoked convulsions. "
03/01/2015 - "Histologic examination of particle-exposed calvariae demonstrated that MTX prevented accumulation of an inflammatory infiltrate at the site of particle implantation, increased the number of osteoblasts, and reduced the number of osteoclasts at the site of inflammation, an effect that was reversed by treatment with ZM241385. "
11/01/2013 - "Adenosine A2A receptors participate in some of the anti-inflammatory effects of CBD, as the A2A antagonist ZM241385 partially blocks the protective effects of CBD in the initial stages of inflammation. "
12/01/2012 - "Our results also demonstrated that A(2A) and A(2B) receptors seem to mediate the adenosine and inosine effects observed, since pretreatment with selective antagonists of adenosine A(2A) (ZM241385) and A(2B) (alloxazine) receptors, reverted the inhibitory effects of adenosine and inosine in pleural inflammation. "
07/31/2003 - "The synergism was more evident when rats were pretreated with a subthreshold dose of ZM 241385 (1.55 micromol/kg) that was unable to modify catalepsy parameters when applied alone, but produced a significant reduction in catalepsy intensity and an increase in catalepsy latency when administered with THP. "
11/01/2010 - "An agonist of A2A receptors CGS 21680 exhibits an anticonvulsant action only in the dose-inducing catalepsy; an A2A antagonist ZM 241385 moderately suppressed tonic phase of GTCS only in 12-day-old animals. "
02/01/2009 - "CSC (1 mg/kg) and ZM 241385 (3 mg/kg) decreased haloperidol (0.5 mg/kg)-induced catalepsy, while at low doses of 0.1 and 0.3 mg/kg, respectively, they did not display an effect. "
07/31/2003 - "Catalepsy was unaffected by a combination of equimolar, subthreshold doses of DPCPX (1.55 micromol/kg) and ZM 241385 (1.55 micromol/kg). "
07/31/2003 - "In contrast, an equimolar dose of the selective adenosine A(2A) antagonist 4-(2-[7-amino-2-(2-furyl)1,2,4-triazolo[2,3-a]-[1,3,5]triazin-5-ylamino]ethyl)phenol (ZM 241385) (5.15 micromol/kg) produced a significant reduction of catalepsy intensity and increased catalepsy latency. "
10/01/2012 - "We found that application of the selective adenosine A2AR antagonist ZM241385 decreased scar size and enhanced the tensile strength of the scar. "
10/01/2012 - "Here, we examined the effect of pharmacological blockade of A2AR, with the selective adenosine A2AR-antagonist ZM241385 (2.5 mg/ml), in a murine model of scarring that mimics human scarring. "
10/01/2012 - "Within the scar itself, collagen alignment and composition (marked reduction in collagen 3), but not periostin, biglycan, or fibronectin accumulation, was improved by application of ZM241385. "
|1.||Adenosine A2A Receptor (Adenosine A2A Receptors)
|3.||Phenol (Carbolic Acid)
|9.||Purinergic P1 Receptors (Adenosine Receptor)
|10.||Caffeine (No Doz)