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CNI 1493

macrophage-deactivating agent used to treat experimental autoimmune encephalomyelitis in mice; a tetravalent guanylhydrazone; structure given in first source
Also Known As:
CNI-1493; N,N'-bis(3,5-diacetylphenyl)decanediamide tetrakis(amidinohydrazone) tetrahydrochloride; semapimod
Networked: 54 relevant articles (11 outcomes, 10 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Tracey, K J: 5 articles (12/2001 - 07/2000)
2. Al-Abed, Yousef: 4 articles (01/2015 - 07/2008)
3. Hauber, Joachim: 3 articles (01/2012 - 05/2008)
4. Plasse, Terry: 3 articles (06/2010 - 01/2002)
5. Tracey, Kevin J: 3 articles (01/2006 - 03/2002)
6. Symons, Marc: 2 articles (01/2015 - 01/2014)
7. Bacher, Michael: 2 articles (01/2013 - 07/2008)
8. Kaiser, Annette: 2 articles (01/2012 - 05/2008)
9. Hauber, Ilona: 2 articles (05/2011 - 05/2008)
10. Meier, Chris: 2 articles (05/2011 - 05/2008)

Related Diseases

1. Inflammation
2. Septic Shock (Toxic Shock Syndrome)
3. Hyperamylasemia
4. Arthritis (Polyarthritis)
5. Crohn Disease (Crohn's Disease)

Related Drugs and Biologics

1. Interleukin-2 (IL2)
2. Biological Markers (Surrogate Marker)
3. Carrageenan
4. Amylases
5. Cytokines
6. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
7. Interleukin-6 (Interleukin 6)
8. Protein Kinases (Protein Kinase)
9. Phosphotransferases (Kinase)
10. fluorocitrate

Related Therapies and Procedures

1. Vagotomy
2. Intraperitoneal Injections
3. Stents
4. Homologous Transplantation (Allograft)
5. Heterologous Transplantation (Xenotransplantation)