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NIP 502

structure in first source

Also Known As:

4-chloro-5-(3-ethoxy-4-methoxybenzylamino)-3-(2H)-pyridazinone; NIP-502

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Benzylamines: 10
    - NIP 502: 1
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzyl Compounds: 2
        Benzylamines: 10
        NIP 502: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridazines: 11
    - NIP 502: 1

Related Diseases

1.	Respiratory Hypersensitivity 05/01/1995 - "NIP-502 improved ovalbumin (OA)-induced airway hyperresponsiveness to acetylcholine and inhibited the OA-induced increase in the number of inflammatory leukocytes in the bronchoalveolar lavage fluid. "
2.	Asthma (Bronchial Asthma) 05/01/1995 - "Because of its effectiveness against a variety of bronchial responses, NIP-502 may be useful in the treatment of bronchial asthma."
3.	Hypersensitivity (Allergy) 05/01/1995 - "Effects of NIP-502 on antigen-induced bronchial responses and allergic reactions in animal models." 05/01/1995 - "NIP-502 also showed an inhibitory effect on the passive cutaneous anaphylactic reaction in rats but did not inhibit the reversed cutaneous anaphylactic reaction, reversed Arthus reaction or delayed type hypersensitivity reaction. " 05/01/1995 - "We examined the effect of a newly synthesized pyridazinone derivative, NIP-502 [4-chloro-5-(3-ethoxy)-4-phenoxybenzamine)-3(2H)-pyridazinone], on antigen-induced bronchial responses and allergic reactions in several animal models. "
4.	Arthus Reaction 05/01/1995 - "NIP-502 also showed an inhibitory effect on the passive cutaneous anaphylactic reaction in rats but did not inhibit the reversed cutaneous anaphylactic reaction, reversed Arthus reaction or delayed type hypersensitivity reaction. "
5.	Anaphylaxis (Anaphylactic Shock) 05/01/1995 - "NIP-502 also showed an inhibitory effect on the passive cutaneous anaphylactic reaction in rats but did not inhibit the reversed cutaneous anaphylactic reaction, reversed Arthus reaction or delayed type hypersensitivity reaction. "

Related Drugs and Biologics

1.	Ovalbumin
2.	Acetylcholine (Acetylcholine Chloride)
3.	Phenoxybenzamine
4.	Antigens