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NIP 502
structure in first source
Also Known As:
4-chloro-5-(3-ethoxy-4-methoxybenzylamino)-3-(2H)-pyridazinone; NIP-502
Networked:
1
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amines: 4871
Benzylamines: 10
NIP 502: 1
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Benzene Derivatives: 17
Benzyl Compounds: 2
Benzylamines: 10
NIP 502: 1
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyridazines: 11
NIP 502: 1
Related Diseases
1.
Respiratory Hypersensitivity
05/01/1995 - "
NIP-502 improved ovalbumin (OA)-induced airway hyperresponsiveness to acetylcholine and inhibited the OA-induced increase in the number of inflammatory leukocytes in the bronchoalveolar lavage fluid.
"
2.
Asthma (Bronchial Asthma)
05/01/1995 - "
Because of its effectiveness against a variety of bronchial responses, NIP-502 may be useful in the treatment of bronchial asthma.
"
3.
Hypersensitivity (Allergy)
05/01/1995 - "
Effects of NIP-502 on antigen-induced bronchial responses and allergic reactions in animal models.
"
05/01/1995 - "
NIP-502 also showed an inhibitory effect on the passive cutaneous anaphylactic reaction in rats but did not inhibit the reversed cutaneous anaphylactic reaction, reversed Arthus reaction or delayed type hypersensitivity reaction.
"
05/01/1995 - "
We examined the effect of a newly synthesized pyridazinone derivative, NIP-502 [4-chloro-5-(3-ethoxy)-4-phenoxybenzamine)-3(2H)-pyridazinone], on antigen-induced bronchial responses and allergic reactions in several animal models.
"
4.
Arthus Reaction
05/01/1995 - "
NIP-502 also showed an inhibitory effect on the passive cutaneous anaphylactic reaction in rats but did not inhibit the reversed cutaneous anaphylactic reaction, reversed Arthus reaction or delayed type hypersensitivity reaction.
"
5.
Anaphylaxis (Anaphylactic Shock)
05/01/1995 - "
NIP-502 also showed an inhibitory effect on the passive cutaneous anaphylactic reaction in rats but did not inhibit the reversed cutaneous anaphylactic reaction, reversed Arthus reaction or delayed type hypersensitivity reaction.
"
Related Drugs and Biologics
1.
Ovalbumin
2.
Acetylcholine (Acetylcholine Chloride)
3.
Phenoxybenzamine
4.
Antigens