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L 744832

a CaaX peptidomimetic; a specific farnesyl-protein transferase inhibitor; structure given in first source
Also Known As:
2-(2-(2-amino-3-mercapto)propylamino-3-methyl)pentyloxy-3-phenylpropionylmethionine sulfone isopropyl ester; L 744,832; L-744,832; L-744832
Networked: 16 relevant articles (2 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Kohl, N E: 2 articles (05/2000 - 01/2000)
2. Refaeli, Yosef: 1 article (01/2008)
3. Field, Kenneth A: 1 article (01/2008)
4. Bishop, J Michael: 1 article (01/2008)
5. Charoenthongtrakul, Soratree: 1 article (01/2008)
6. Samplonius, Douwe F: 1 article (04/2006)
7. Helfrich, Wijnand: 1 article (04/2006)
8. de Leij, Lou F M H: 1 article (04/2006)
9. Bremer, Edwin: 1 article (04/2006)
10. ten Cate, Bram: 1 article (04/2006)

Related Diseases

1. Neoplasms (Cancer)
2. Lymphoma (Lymphomas)
3. Astrocytoma (Pilocytic Astrocytoma)
4. Colonic Neoplasms (Colon Cancer)
5. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. 70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)
2. Sirolimus (Rapamycin)
3. Farnesyltranstransferase (Farnesyltransferase)
4. Paclitaxel (Taxol)
5. Fluorouracil (Carac)
6. Butyrates (Butyrate)
7. Transferases
8. Cyclin B1
9. Proteasome Endopeptidase Complex (Proteasome)
10. Transforming Growth Factor alpha (TGF-alpha)

Related Therapies and Procedures

1. Radiotherapy
2. Heterologous Transplantation (Xenotransplantation)
3. Transplantation (Transplant Recipients)
4. Aftercare (After-Treatment)