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sulfobacin B

a von Willebrand factor receptor antagonist; isolated from Chryseobacterium sp. NR 2993; structure given in first source

Also Known As:

3-hydroxy-15-methyl-2-(13-methyltetradecanamido)hexadecanesulfonic acid

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Acyclic Hydrocarbons
    - Alkanes: 241
      - Alkanesulfonic Acids
        sulfobacin B: 1
- Sulfur Compounds: 278
  - Sulfur Acids
    - Sulfonic Acids: 1605
      - Alkanesulfonic Acids
        sulfobacin B: 1

Experts

1.	Azuma, Takeshi: 1 article (11/2010)
2.	Maeda, Jun: 1 article (11/2010)
3.	Mizushina, Yoshiyuki: 1 article (11/2010)
4.	Nishida, Masayuki: 1 article (11/2010)
5.	Takikawa, Hirosato: 1 article (11/2010)
6.	Yoshida, Hiromi: 1 article (11/2010)
7.	Yoshida, Masaru: 1 article (11/2010)

Related Diseases

1.

Inflammation (Inflammations)

11/01/2010 - "These results indicate that sulfobacin B is a potential chemotherapeutic agent for inflammation."
11/01/2010 - "In an in vivo mouse model of LPS-induced acute inflammation, the intraperitoneal injection of sulfobacin B to mice led to the suppression of serum TNF-α production. "
11/01/2010 - "Inhibitory effects of sulfobacin B on DNA polymerase and inflammation."
11/01/2010 - "However, sulfobacin B did not influence the activity of plant or prokaryotic pols, or that of the other DNA metabolic enzymes such as primase of pol α, RNA polymerase, polynucleotide kinase or deoxyribonuclease I. As we previously found a positive relationship between pol λ inhibition and anti-inflammation, we examined whether sulfobacin B could inhibit inflammatory responses. "

Related Drugs and Biologics

1.	DNA Primase (Primase)
2.	DNA-Directed RNA Polymerases (RNA Polymerase)
3.	Polynucleotide 5'-Hydroxyl-Kinase (Kinase, Polynucleotide)
4.	Enzymes
5.	DNA-Directed DNA Polymerase (Polymerases, DNA)
6.	DNA (Deoxyribonucleic Acid)
7.	Deoxyribonuclease I (Nickase)

Related Therapies and Procedures

1.	Intraperitoneal Injections