serum tumorlytic factor

a tumor necrosis factor homolog induced in serum of mice injected with T-cell mitogen from Corynebacterium kutscheri; partial amino acid sequence given in first source

Also Known As:

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Carneiro-Lobo, T C: 1 article (09/2012)
2.	Disse, J: 1 article (09/2012)
3.	Francischetti, I M B: 1 article (09/2012)
4.	Monteiro, R Q: 1 article (09/2012)
5.	Ostergaard, H: 1 article (09/2012)
6.	Ruf, W: 1 article (09/2012)
7.	Schaffner, F: 1 article (09/2012)
8.	Booth, C J: 1 article (04/2011)
9.	Cheng, J: 1 article (04/2011)
10.	Duanmu, J: 1 article (04/2011)

Related Diseases

1.	Neoplasms (Cancer) 09/01/2012 - "In contrast to human VIIa, Ixolaris was a poor inhibitor of murine TF-FVIIa signaling and did not attenuate PAR2-dependent tumor growth in a syngeneic mouse model of breast cancer progression. " 07/01/2007 - "To better define the relationship between tumor cell-associated TF and circulating hemostatic factors in malignancy, we generated a set of C57Bl/6-derived tumor lines genetically lacking TF, expressing wild-type murine TF, or expressing a mutant TF lacking the cytoplasmic domain. "
2.	Breast Neoplasms (Breast Cancer) 09/01/2012 - "In contrast to human VIIa, Ixolaris was a poor inhibitor of murine TF-FVIIa signaling and did not attenuate PAR2-dependent tumor growth in a syngeneic mouse model of breast cancer progression. " 04/26/2011 - "The TF expression by the MCF-7/MDR breast cancer cells and tumour VECs in MCF-7/MDR tumours from mice was determined separately by flow cytometry and immunohistochemistry using anti-human or anti-murine TF antibodies. "
3.	Venous Thrombosis (Deep-Vein Thrombosis) 02/13/2009 - "Andro-treated and p50 null mice both exhibited blunted TF expression and reduced venous thrombosis, which were recapitulated by an anti-murine TF antibody in vivo. "
4.	Sepsis (Septicemia) 02/01/2006 - "We developed and validated a rabbit anti-murine TF peptide antiserum to localize TF protein in a murine sepsis model. "
5.	Thrombosis (Thrombus) 04/01/1997 - "This hypothesis was supported by several lines of evidence: (a) MP depletion before hypoxia reduced thrombosis, as measured by reduced 125I-fibrin/fibrinogen deposition and reduced accumulation of cross-linked fibrin by immunoblot; (b) isolated murine MPs demonstrated increased TF immunostaining when exposed to hypoxia; and (c) administration of an anti-rabbit TF antibody that cross-reacts with murine TF decreased 125I-fibrin/fibrinogen accumulation and cross-linked fibrin accumulation in response to hypoxia in vivo. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Peptides (Polypeptides)
3.	Hemostatics (Antihemorrhagics)
4.	Fibrinogen (Factor I)
5.	Fibrin
6.	Antibodies