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osemozotan

5-HT(1A) receptor agonist

Also Known As:

5-(3-((1,4-benzodioxan-2-ylmethyl)amino)propoxy)-1,3-benzodioxole hydrochloride; MKC 242; MKC-242

Networked: 6 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Dioxanes
    - osemozotan: 6
  - Dioxoles
    - osemozotan: 6

Experts

1.	Matsuda, Toshio: 3 articles (11/2013 - 09/2006)
2.	Ago, Yukio: 2 articles (11/2013 - 09/2006)
3.	Asada, Kazuki: 1 article (11/2013)
4.	Hasebe, Shigeru: 1 article (11/2013)
5.	Higashino, Kosuke: 1 article (11/2013)
6.	Horiguchi, Naotaka: 1 article (11/2013)
7.	Kita, Yuki: 1 article (11/2013)
8.	Takuma, Kazuhiro: 1 article (11/2013)
9.	Abe, Michikazu: 1 article (09/2006)
10.	Baba, Akemichi: 1 article (09/2006)

Related Diseases

1.	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 07/01/1998 - "These findings suggest that stimulation of 5-HT1A receptors reduces stress-induced defecation but not spontaneous and 5-HT-induced defecation and that MKC-242 may be useful for the treatment of irritable bowel syndrome."
2.	Schizophrenia (Dementia Praecox) 09/01/2006 - "These results suggest that prefrontal 5-HT release is involved at least partly in the effects of osemozotan on single and repeated METH-induced behavioral effects in mice, and imply that the 5-HT1A receptors may have a potential therapeutic value in the remission of schizophrenia."
3.	Substance-Related Disorders (Drug Abuse) 01/01/2013 - "This review summarizes the neuropharmacology of the 5-HT1A receptor, focusing on our studies using osemozotan, and suggests that the 5-HT1A receptor may be a target molecule for the treatment of psychiatric disorders, pain, and drug dependence. "
4.	Pain (Aches) 01/01/2013 - "This review summarizes the neuropharmacology of the 5-HT1A receptor, focusing on our studies using osemozotan, and suggests that the 5-HT1A receptor may be a target molecule for the treatment of psychiatric disorders, pain, and drug dependence. "
5.	Mental Disorders (Mental Disorder) 01/01/2013 - "This review summarizes the neuropharmacology of the 5-HT1A receptor, focusing on our studies using osemozotan, and suggests that the 5-HT1A receptor may be a target molecule for the treatment of psychiatric disorders, pain, and drug dependence. "

Related Drugs and Biologics

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3.	Corticosterone

Related Therapies and Procedures

1.	Spinal Injections