|1.||Tang, Deliang: 6 articles (01/2013 - 09/2002)|
|2.||Rundle, Andrew: 5 articles (01/2013 - 09/2002)|
|3.||Santella, Regina M: 4 articles (04/2009 - 05/2002)|
|4.||Poirier, Miriam C: 4 articles (06/2008 - 03/2004)|
|5.||Rybicki, Benjamin A: 3 articles (01/2013 - 12/2004)|
|6.||Gammon, Marilie D: 3 articles (04/2009 - 08/2002)|
|7.||Eng, Sybil M: 3 articles (04/2009 - 08/2002)|
|8.||Teitelbaum, Susan L: 3 articles (04/2009 - 08/2002)|
|9.||Neugut, Alfred I: 3 articles (04/2009 - 08/2002)|
|10.||Baird, William M: 3 articles (06/2008 - 01/2004)|
02/01/2008 - "Associations between PAH-DNA adduct levels and both cancer risk and developmental deficits have been seen in previous experimental and epidemiologic studies. "
11/01/2007 - "Therefore, PAH-DNA adduct formation as measured by this methodology did not appear related to the increased risk of cervical precancer and cancer among carcinogenic HPV-infected smokers."
12/15/2004 - "In prostate tumor cells, decreased cellular differentiation and increased tumor proliferation may reduce PAH-DNA adduct levels."
12/15/2004 - "PSA levels were inversely associated with PAH-DNA adduct levels in tumor cells (P = 0.009). "
12/15/2004 - "Tumors that involved 10% or less of the prostate gland had significantly higher PAH-DNA adduct levels than tumors that involved 15 to 20% of the prostate gland (P = 0.004). "
|2.||Lung Neoplasms (Lung Cancer)
03/01/1993 - "Recently we showed that total PAH-DNA adduct levels in WBC from lung cancer patients were much higher than those generally found in healthy smokers.(ABSTRACT TRUNCATED AT 250 WORDS)"
08/15/1989 - "These results are consistent with a genetically determined enhancement of PAH-DNA adduct formation in leukocytes of lung cancer cases which is evident in current smokers. "
11/01/1994 - "Additional studies should be conducted to confirm a possible role for vitamin E in PAH-DNA adduct formation and to explore further the possible roles of vitamin A, beta-carotene and vitamin C in modulating adduct formation and lung cancer risk."
|3.||Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
07/01/2007 - "Furthermore, leukocyte PAH-DNA adduct levels have been demonstrated to increase in response to charbroiled red meat intake but to date there have been no studies that have investigated the relationship between leukocyte PAH-DNA adduct levels and risk of colorectal adenoma. "
07/01/2007 - "In addition, a comparison of the lowest quartile for PAH-DNA adduct level with the highest quartile yielded an OR of 2.8 (95% CI, 1.2-6.5; P(trend) = 0.048) for risk of colorectal adenoma. "
07/01/2007 - "We investigated the relation of leukocyte PAH-DNA adduct formation and colorectal adenoma in a clinic-based case-control study of colorectal adenomas. "
07/01/2007 - "There was a positive association between PAH-DNA adduct level and adenoma prevalence: each unit increase in PAH-DNA adduct level (per 10(8) nucleotides) was associated with an odds ratio (OR) of 1.5 [95% confidence interval (CI), 1.1-2.2]. "
07/01/2007 - "Leukocyte PAH-DNA adduct levels were higher among colorectal adenoma cases (median, 1.4 adducts per 10(8) nucleotides) than polyp-free controls (median, 1.2 adducts per 10(8) nucleotides) (P = 0.02). "
|5.||Breast Neoplasms (Breast Cancer)
04/01/2009 - "Using Cox proportional hazards models and controlling for age at diagnosis, we did not find evidence that all-cause mortality (hazard ratio (HR)=0.88; 95% confidence interval (CI): 0.57-1.37), or breast cancer mortality (HR=1.20; 95% CI: 0.63-2.28) was strongly associated with detectable PAH-DNA adduct levels compared with non-detectable adducts; additionally, no dose-response association was observed. "
04/01/2009 - "Among the 722 cases with PAH-DNA adduct measurements, 97 deaths (13.4%) from all causes and 54 deaths (7.5%) due to breast cancer were reported to the National Death Index (NDI) by December 31, 2002. "
12/01/2007 - "The presence of at least one variant allele (GA or AA) in FAS1377 was associated with a 36% increase in breast cancer risk among those with detectable PAH-DNA adduct levels [odds ratio (OR) = 1.36, 95% confidence interval (CI) = 1.01-1.83]. "
03/01/2003 - "Sulfotransferase 1A1 (SULT1A1) polymorphism, PAH-DNA adduct levels in breast tissue and breast cancer risk in a case-control study."
08/01/2002 - "These data indicate that PAH-DNA adduct formation may influence breast cancer development, although the association does not appear to be dose dependent and may have a threshold effect."
|1.||DNA (Deoxyribonucleic Acid)
|2.||Cytochrome P-450 CYP1A1 (CYP1A1)
|3.||Cytochrome P-450 CYP2D6 (CYP2D6)
|4.||beta Carotene (Betacarotene)
|6.||Vitamin A (Retinol)
|7.||Ascorbic Acid (Vitamin C)
|9.||Cytochrome P-450 Enzyme System (Cytochrome P450)