8-nitroguanine

03/29/2016 - "8-Nitroguanine (8-nitroG) is a mutagenic DNA lesion formed during inflammation. "
08/01/2010 - "8-Nitroguanine is a mutagenic DNA lesion formed during chronic inflammation. "
03/01/2010 - "8-Nitroguanine is a mutagenic DNA lesion formed during chronic inflammation. "
01/01/2009 - "8-Nitroguanine immunoreactivity, which was observed mainly in the nuclei of stomach epithelium, increased with the severity of inflammation. "
01/01/2009 - "8-Nitroguanine is a mutagenic nitrative DNA lesion formed during inflammation. "

03/01/2010 - "Moreover, strong 8-nitroguanine formation in tumor tissues was closely associated with a poor prognosis. "
11/01/2007 - "Little or no immunoreactivity of 8-nitroguanine and HIF-1alpha was observed in adjacent non-tumor tissues. "
11/01/2007 - "8-Nitroguanine formation was predominantly observed in the nuclei of tumor cells and inflammatory cells in tumor tissues, while HIF-1alpha was expressed in the cytoplasm and nuclei of tumor cells. "
11/01/2007 - "The aim of this study was to evaluate the impact of 8-nitroguanine formation and HIF-1alpha expression on the prognosis of patients with inflammation-related cancer. "
02/15/2006 - "This is the first report to show that 8-nitroguanine is present in human urine and the methodology developed can be used to study the pathogenic roles of this adduct in the etiology of cancers associated with cigarette smoking and inflammation."

03/01/2010 - "In an earlier publication, our group reported the results of an immunohistochemical analysis of animals infected with the liver fluke Opisthorchis viverrini and demonstrated for the first time that 8-nitroguanine was formed at the sites of carcinogenesis. "
05/01/2006 - "Interestingly, 8-nitroguanine was formed at the sites of carcinogenesis regardless of etiology. "
07/01/2007 - "The present study sought to examine if 8-nitroguanine, a mutagenic nitrative DNA lesion formed during inflammation, contributes to cervical carcinogenesis. "
03/27/2018 - "8-Nitroguanine (8-nitroG) is a mutagenic DNA lesion formed during inflammation and may participate in carcinogenesis. "
04/15/2012 - "8-Nitroguanine is a mutagenic DNA lesion formed during inflammation and may play a role in CNT-induced carcinogenesis. "

05/01/2006 - "An immunofluorescence labeling study demonstrated that 8-nitroguanine was strongly formed in gastric gland epithelial cells in gastritis patients with H. "
06/25/2004 - "A double immunofluorescence labeling study demonstrated that the level of 8-nitroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) apparent in gastric gland epithelium was significantly higher in gastritis patients with H. "

01/01/2016 - "Moreover, 8-nitroguanine was formed in Oct3/4-positive stem cells in SH-associated bladder cancer tissues, and in Oct3/4- and CD133-positive stem cells in OV-associated cholangiocarcinoma tissues. "
01/01/2013 - "Moreover, 8-nitroguanine was formed in Oct3/4-positive stem cells in SH-associated bladder cancer tissues and in Oct3/4- and CD133-positive stem cells in OV-associated cholangiocarcinoma tissues. "
09/26/2003 - "The mechanisms of 8-oxodG and 8-nitroguanine formation via O2*- and NO production triggered by OV infection were discussed in relation to cholangiocarcinoma development."
08/14/2005 - "We investigated the relation of the formation of 8-nitroguanine and 8-oxodG and the expression of hypoxia-inducible factor-1alpha (HIF-1alpha) with tumor invasion in 37 patients with intra-hepatic cholangiocarcinoma. "
10/20/2018 - "Our previous studies demonstrated the formation of 8-oxodG and 8-nitroguanine in the tissues of cancer and precancerous lesions due to infection (e.g., Opisthorchis viverrini-related cholangiocarcinoma, Schistosoma haematobium-associated bladder cancer, Helicobacter pylori-infected gastric cancer, human papillomavirus-related cervical cancer, Epstein-Barr virus-infected nasopharyngeal carcinoma) and pro-inflammatory factors (e.g., asbestos, nanomaterials, and inflammatory diseases such as Barrett's esophagus and oral leukoplakia). "