filenadol

Also Known As:

1-(3',4'-methylenedioxyphenyl)-1-morpholinopropan-2-ol; d,l-erythro-1-(3',4'-methylenedioxyphenyl)-1-morpholinopropan-2-ol

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Pain (Aches) 01/01/1995 - "Antinociceptive activity of filenadol on inflammatory pain." 01/01/1995 - "The late phase of formalin-induced pain response in mice was prevented by filenadol, without affecting the oedema. "
2.	Hyperalgesia 01/01/1995 - "The novel analgesic filenadol (d, 1-erythro-1-(3',4'-methylenedioxyphenyl)-1- morpholinopropan-2-ol) inhibited phenyl-p-benzoquinone-induced writhing in mice with ID50 values of 68.8 (p.o.), 1.67 (i.v.) and 0.48 (i.c.v.) mg/kg. Hyperalgesia induced by arachidonic acid, PGE2 or LTB4 in this test was also decreased by filenadol (ID50 = 24.4, 3.7 and 50.1 mg/kg p.o., respectively). "