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EM 219
an antiestrogen
Also Known As:
EM-219; N-butyl,N-methyl-11-(3',17'beta-dihydroxy-17'alpha-ethinylestra-1',3',5'(10'),14'-tetraen-7'alpha-yl)undecanamide
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Polycyclic Compounds: 6
Fused-Ring Compounds
Steroids: 70059
Estranes
Estrenes
EM 219: 1
Related Diseases
1.
Neoplasms (Cancer)
05/01/1995 - "
The present data show that combination of the pure antiestrogen EM-219 with MPA exerts a greater reduction in DMBA-induced mammary tumor growth and intratumoral E2 levels stimulated by E1 than either compound used alone.
"
05/01/1995 - "
MPA (1.5 mg, twice daily) partially reversed the stimulatory effect of E1 to 66.0 +/- 9.0%, while the antiestrogen EM-219 (40 micrograms, twice daily) decreased tumor size to 70.0 +/- 10%.
"
2.
Carcinoma (Carcinomatosis)
05/01/1995 - "
Inhibitory effects of medroxyprogesterone acetate (MPA) and the pure antiestrogen EM-219 on estrone (E1)-stimulated growth of dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat.
"
Related Drugs and Biologics
1.
Estrogen Receptor Modulators (Antiestrogen)
2.
Medroxyprogesterone Acetate (Depo-Provera)
3.
Estrone
4.
anthracene