dehydroilludin M

RN given for (R)-isomer; structure in first source

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

1.	Carcinoma (Carcinomatosis) 05/01/1995 - "Dehydroilludin M retained the in vitro relative selective cytotoxicity for carcinomas and myeloid leukemia cell lines noted with the parent illudin compounds. " 05/01/1995 - "The efficacy of dehydroilludin M in the MV522 lung carcinoma model exceeded that of 9 known anticancer drugs, and equaled that of mitomycin C. "
2.	Neoplasms (Cancer) 05/01/1995 - "One analog, dehydroilludin M, inhibited xenograft growth and prolonged life span of tumor bearing animals, when administered IP or IV, whereas the parent Illudin S compound was ineffective. "
3.	Myeloid Leukemia (Leukemia, Myelocytic) 05/01/1995 - "Dehydroilludin M retained the in vitro relative selective cytotoxicity for carcinomas and myeloid leukemia cell lines noted with the parent illudin compounds. "