15-hydroxyeicosatrienoic acid

the 15-lipoxygenase product of dihomogammalinolenic acid; inhibits the biosynthesis of the proinflammatory eicosanoids leukotriene B4 (LTB4) and 12-hydroxyeicosatetraenoic acid

Also Known As:

15-HETrE

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - Eicosanoids: 3262
      - Arachidonic Acids: 122
        Hydroxyeicosatetraenoic Acids: 318
        15-hydroxyeicosatrienoic acid: 3
    - Essential Fatty Acids: 734
      - Arachidonic Acids: 122
        Hydroxyeicosatetraenoic Acids: 318
        15-hydroxyeicosatrienoic acid: 3

Experts

1.	Pham, H: 1 article (08/2000)
2.	Xi, S: 1 article (08/2000)
3.	Ziboh, W A: 1 article (08/2000)

Related Diseases

1.	Pneumonia (Pneumonitis) 07/01/1997 - "Taken together, data from these studies suggest that dietary GLA-containing oil contributes to tissue elevation of PGE1 and 15-HETrE, which in vivo may attenuate lung inflammation and fibrosis."
2.	Fibrosis (Cirrhosis) 07/01/1997 - "Taken together, data from these studies suggest that dietary GLA-containing oil contributes to tissue elevation of PGE1 and 15-HETrE, which in vivo may attenuate lung inflammation and fibrosis."
3.	Hyperplasia 08/01/2000 - "15-HETrE, on the other hand, reversed the DHA-induced epidermal hyperplasia, and upregulated epidermal AP-1 expression. "
4.	Ischemic Stroke 10/04/2023 - "Administration of 15-HETrE enhanced functional recovery after ischemic stroke. "

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