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cytomegalovirus US3 protein

HCMV - human cytomegalovirus; a type I membrane protein, prevents maturation of class I major histocompatibility complex (MHC) molecules by retaining them in the endoplasmic reticulum (ER) and thus helps inhibit antigen presentation to cytotoxic T cells; bind to class I MHC molecules in a transient fashion but retain them very efficiently in the ENDOPLASMIC RETICULUM; has been sequenced
Also Known As:
US3 protein, cytomegalovirus
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