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Zeneca ZD 6169

an ATP-sensitive potassium channel opener; structure given in first source

Also Known As:

ZD 6169; ZD-6169; ZD6169; Zeneca ZD6169

Networked: 4 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133

Experts

1.	Andersson, Karl-Erik: 1 article (09/2002)
2.	Pandita, Raj Kumar: 1 article (09/2002)
3.	Abdel-Karim, Aly M: 1 article (08/2002)
4.	Bialecki, Russell A: 1 article (08/2002)
5.	Elhilali, Mostafa M: 1 article (08/2002)

Related Diseases

1.	Overactive Urinary Bladder (Overactive Bladder) 08/01/2002 - "ZD6169 and ZD0947 are effective treatment for detrusor hyperreflexia after spinal cord injury and they may provide alternative treatment options for overactive bladder. "
2.	Spinal Cord Injuries (Spinal Cord Injury) 08/01/2002 - "ZD6169 and ZD0947 are effective treatment for detrusor hyperreflexia after spinal cord injury and they may provide alternative treatment options for overactive bladder. " 08/01/2002 - "We tested the efficacy of the 2 adenosine triphosphate dependent K channel openers ZD6169 and ZD0947 on detrusor hyperreflexia after spinal cord injury in rats. "
3.	Abnormal Reflex (Hyperreflexia) 08/01/2002 - "Detrusor hyperreflexia resolved in 66% of the animals that received ZD6169 for 1 week at either dose. " 08/01/2002 - "ZD6169 and ZD0947 are effective treatment for detrusor hyperreflexia after spinal cord injury and they may provide alternative treatment options for overactive bladder. " 08/01/2002 - "We tested the efficacy of the 2 adenosine triphosphate dependent K channel openers ZD6169 and ZD0947 on detrusor hyperreflexia after spinal cord injury in rats. "
4.	Urge Urinary Incontinence (Urge Incontinence) 11/08/1996 - "ZD6169, 41(S), has been selected into development for the treatment of urge urinary incontinence."
5.	Urinary Incontinence 10/27/1999 - "The effect of the K(ATP) channel opener ZD6169 [(S)-N-(4-benzoyl-phenyl)-3,3, 3-trifluoro-2-hydroxy-2-methyl-propionamide] currently under development for the treatment of urinary incontinence was explored in acutely isolated adult feline ventricular myocytes. "

Related Drugs and Biologics

1.	Adenosine Triphosphate (ATP)
2.	ZD0947
3.	propionamide