human PMS2 protein

RefSeq NM_000535

Also Known As:

PMS2 protein, human; PMS2 postmeiotic segregation increased 2 (S. cerevisiae) protein, human; hPMS2 protein, human; mismatch repair gene PMS2; post meiotic segregation increased 2 protein, human

Networked: 9 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	van der Klift, Heleen M: 2 articles (07/2012 - 02/2006)
2.	Brunetti-Pierri, Nicola: 1 article (01/2014)
3.	Canta, Luigi: 1 article (01/2014)
4.	Cappuccio, Gerarda: 1 article (01/2014)
5.	Carella, Massimo: 1 article (01/2014)
6.	Chen, Haiquan: 1 article (01/2014)
7.	Ciancia, Giuseppe: 1 article (01/2014)
8.	De Crescenzo, Agostina: 1 article (01/2014)
9.	Fang, Rong: 1 article (01/2014)
10.	Gao, Bin: 1 article (01/2014)

Related Diseases

1.	Carcinoma (Carcinomatosis) 02/23/2010 - "The aim of this study was to determine the expression of PMS2 in cervical carcinoma and evaluate the significance of mismatch repair gene PMS2 regulated by glycogen synthase kinase 3beta (GSK-3beta) in chemosensitivity. " 02/23/2010 - "Stabilization of mismatch repair gene PMS2 by glycogen synthase kinase 3beta is implicated in the treatment of cervical carcinoma."
2.	Neoplasms (Cancer) 01/01/2014 - "Sequencing analysis of tumor samples as well as histologically normal specimens identified two germline mutations co-existing in the familial cancer syndrome, the mutation of tumor suppressor gene P53 V157D and mismatch repair gene PMS2 R20Q. " 07/01/2012 - "Heterozygous germline mutations in the mismatch repair gene PMS2 predispose carriers for Lynch syndrome, an autosomal dominant predisposition to cancer. " 07/15/2004 - "Mismatch repair gene PMS2: disease-causing germline mutations are frequent in patients whose tumors stain negative for PMS2 protein, but paralogous genes obscure mutation detection and interpretation."
3.	Hereditary Nonpolyposis Colorectal Neoplasms (Hereditary Nonpolyposis Colorectal Cancer) 04/01/2009 - "Recently, it was shown that germline mutations in another mismatch repair gene, PMS2, play a far more important role in Lynch syndrome than initially thought. " 07/01/2012 - "Heterozygous germline mutations in the mismatch repair gene PMS2 predispose carriers for Lynch syndrome, an autosomal dominant predisposition to cancer. "
4.	Colorectal Neoplasms (Colorectal Cancer) 02/01/2006 - "The role of the mismatch repair gene PMS2 in hereditary nonpolyposis colorectal carcinoma (HNPCC) is not fully clarified. "
5.	Medulloblastoma 08/01/2013 - "We describe a 12-year-old girl, simultaneously presenting with colonic adenocarcinoma and medulloblastoma from bialleic deletions in the mismatch repair gene PMS2. "

Related Drugs and Biologics

1.	Glycogen Synthase Kinases
2.	Glycogen Synthase (Synthase I)
3.	Coloring Agents (Dyes)
4.	Mismatch Repair Endonuclease PMS2