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integrin alpha8beta1

promotes attachment, cell spreading & neurite outgrowth on fibronectin

Also Known As:

alpha8beta1 integrin; tensegrin

Networked: 8 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Immunologic Receptors: 9
        Integrins: 14304
        integrin alpha8beta1: 8

Experts

1.	Schnapp, Lynn M: 2 articles (11/2009 - 12/2002)
2.	Thibault, Gaétan: 2 articles (07/2007 - 03/2005)
3.	Zargham, Ramin: 2 articles (07/2007 - 03/2005)
4.	Belin, Andrea Carmine: 1 article (01/2016)
5.	Fardell, Camilla: 1 article (01/2016)
6.	Mehdi, Rawand Naiel: 1 article (01/2016)
7.	Nissbrandt, Hans: 1 article (01/2016)
8.	Ran, Caroline: 1 article (01/2016)
9.	Sydow, Olof: 1 article (01/2016)
10.	Wirdefeldt, Karin: 1 article (01/2016)

Related Diseases

1.	Inflammation (Inflammations) 11/15/2009 - "In this study we show that expression of the fibronectin receptor, integrin alpha8beta1 is decreased in the lung mesenchyme in the same inflammation model suggesting it is required for normal lung development. "
2.	Fibrosis (Cirrhosis) 12/01/2002 - "We previously reported that the integrin alpha8beta1 is expressed by alveolar interstitial cells in normal lung and is upregulated during the development of fibrosis. " 06/01/2000 - "Expression of the integrin alpha8beta1 during pulmonary and hepatic fibrosis." 03/01/2004 - "The coordinate regulation of alpha8beta1 integrin on fibroblasts and ECM proteins raises the possibility that this integrin is implicated in the deposition of matrix components leading to fibrosis."
3.	Neointima 03/01/2005 - "alpha8beta1 Integrin expression in the rat carotid artery: involvement in smooth muscle cell migration and neointima formation." 07/01/2007 - "alpha8beta1 Integrin is up-regulated in the neointima concomitant with late luminal loss after balloon injury."
4.	Neurodegenerative Diseases (Neurodegenerative Disease) 01/01/2016 - "Integrin alpha 8 (ITGA8) encodes the alpha 8 subunit of the integrin alpha8beta1 protein and has recently been suggested as a new candidate gene for Parkinson's disease, an age related neurodegenerative disease with unknown etiology. "
5.	Parkinson Disease (Parkinson's Disease) 01/01/2016 - "Integrin alpha 8 (ITGA8) encodes the alpha 8 subunit of the integrin alpha8beta1 protein and has recently been suggested as a new candidate gene for Parkinson's disease, an age related neurodegenerative disease with unknown etiology. "

Related Drugs and Biologics

1.	Integrin alpha5beta1
2.	Proteins (Proteins, Gene)
3.	Integrins
4.	Phenobarbital (Luminal)
5.	integrin alpha8