amodiaquine quinoneimine

structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Commandeur, Jan N M: 1 article (01/2018)
2.	Hiemstra, Steven: 1 article (01/2018)
3.	Vermeulen, Nico P E: 1 article (01/2018)
4.	Vos, J C: 1 article (01/2018)
5.	Zhang, Yongjie: 1 article (01/2018)
6.	den Braver, Michiel W: 1 article (01/2018)
7.	den Braver-Sewradj, Shalenie P: 1 article (01/2018)
8.	van de Water, Bob: 1 article (01/2018)
9.	Bickley, Jamie F: 1 article (11/2003)
10.	Bray, Patrick G: 1 article (11/2003)

1.	Drug-Related Side Effects and Adverse Reactions 11/06/2003 - "The observed drug toxicity is believed to involve the formation of an electrophilic metabolite, amodiaquine quinoneimine (AQQI), which can bind to cellular macromolecules and initiate hypersensitivity reactions. "
2.	Malaria 01/01/2018 - "Formation of the reactive amodiaquine quinoneimine (AQ-QI) and N-desethylamodiaquine quinoneimine (DEAQ-QI) plays an important role in the toxicity of the anti-malaria drug amodiaquine (AQ). "
3.	Hypersensitivity (Allergy) 11/06/2003 - "The observed drug toxicity is believed to involve the formation of an electrophilic metabolite, amodiaquine quinoneimine (AQQI), which can bind to cellular macromolecules and initiate hypersensitivity reactions. "