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4-hydroxynethyl-furoxan-3-carboxamide
structure given in first source
Also Known As:
CAS 1609; CAS-1609
Networked:
2
relevant articles (
1
outcomes,
1
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Oxazoles: 89
Oxadiazoles: 146
4-hydroxynethyl-furoxan-3-carboxamide: 2
Related Diseases
1.
Heart Failure
04/01/1995 - "
5. In anaesthetized dogs with acute heart failure due to intracoronary injection of microspheres, CAS 1609 (0.3 mg kg-1, i.v.) improved the haemodynamic condition and reduced mortality by 80%.
"
2.
Myocardial Ischemia (Ischemic Heart Diseases)
09/01/1995 - "
In the present study a novel nitric oxide (NO) donor, CAS-1609, was utilized as a means of coronary NO replenishment in a canine model of myocardial ischemia-reperfusion.
"
3.
Necrosis
09/01/1995 - "
Moreover, myocardial necrosis as a percentage of the area at risk was reduced from 28.9 +/- 4.3% in the saline group to 8.5 +/- 2.6% in the CAS-1609 group (P < 0.01), while ischemic zone myeloperoxidase activity, indicative of neutrophil infiltration, was also attenuated by 70% with NO therapy.
"
Related Drugs and Biologics
1.
Nitric Oxide (Nitrogen Monoxide)
2.
Peroxidase (Myeloperoxidase)
Related Therapies and Procedures
1.
Microspheres (Microsphere)
2.
Therapeutics