HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

integrin alphavbeta1

closely related to alpha5beta1 integrin

Also Known As:

alphavbeta1 integrin

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Immunologic Receptors: 9
        Integrins: 14304
        Cytoadhesin Receptors
        Vitronectin Receptors: 9
        integrin alphavbeta1: 5

Experts

1.	Cox, Reagan G: 1 article (02/2009)
2.	Cseke, Gabriella: 1 article (02/2009)
3.	Dermody, Terence S: 1 article (02/2009)
4.	Maginnis, Melissa S: 1 article (02/2009)
5.	Podsiad, Amy B: 1 article (02/2009)
6.	Tollefson, Sharon J: 1 article (02/2009)
7.	Williams, John V: 1 article (02/2009)
8.	Wright, David W: 1 article (02/2009)
9.	Griswold-Prenner, Irene: 1 article (02/2007)
10.	Malinin, Nikolay L: 1 article (02/2007)

Related Diseases

1.	Ovarian Neoplasms (Ovarian Cancer) 01/01/2005 - "On the other hand, fibronectin (FN), a receptor for alphavbeta1 integrin, increased proliferation in all ovarian cancer cell lines studied but only enhanced adhesion in Hey cell line (P<0.05). "
2.	Infections 02/03/2009 - "Integrin alphavbeta1 promotes infection by human metapneumovirus."
3.	Glioma (Gliomas) 01/15/2006 - "Angiopoietin 2 induces glioma cell invasion by stimulating matrix metalloprotease 2 expression through the alphavbeta1 integrin and focal adhesion kinase signaling pathway."
4.	Alzheimer Disease (Alzheimer's Disease) 02/01/2007 - "These results indicate that the alpha2beta1 and alphaVbeta1 integrin signaling pathway may be critical components of neurodegeneration in Alzheimer's disease and that integrins may recognize and be activated by a shared structural motif of polymerizing amyloidogenic proteins."
5.	Adenocarcinoma 11/15/1999 - "Neither the human embryonic kidney 293 cell line, which expresses the alphavbeta1 integrin, nor the human colonic adenocarcinoma HT-29 cell line, which expresses the alphavbeta5 integrin, were able to adhere to OPN; both of these cell lines are deficient in the beta3 subunit. "

Related Drugs and Biologics

1.	Amyloidogenic Proteins
2.	Focal Adhesion Protein-Tyrosine Kinases
3.	Metalloproteases (Metalloproteinases)
4.	Angiopoietin-2
5.	Integrins
6.	Fibronectins (Fibronectin)
7.	integrin alphaVbeta5