S 16118

a nonapeptide; a bradykinin B2 receptor antagonist

Also Known As:

S-16118; bradykinin, p-guanidobenzoyl-(hydroxyprolyl(3)-thienylalanyl(5)-tetrahydroisoquinolinecarbonyl(7)-octahydroindolecarbonyl(8))-; p-guanidobenzoyl-(Hyp(3)-Thi(5)-D-Tic(7)-Oic(8))BK

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Hypovolemia 06/01/1995 - "S 16118 (100 nmol/kg s.c.) prevented the hypotension, the pancreatic edema and the hypovolemia and induced a marked increase in the serum lipase and amylase activity. "
2.	Neurogenic Inflammation 06/01/1995 - "Aerosolization of S 16118 (5 x 10(-3) M for 20 sec), 4 min before vagus nerve stimulation, induced a 60% decrease in the Evans blue extravasation, demonstrating the modulatory role of BK in neurogenic inflammation. "
3.	Inflammation (Inflammations) 06/01/1995 - "The effects of S 16118 (p-guanidobenzoyl-[Hyp3,Thi5,D-Tic7, Oic8]bradykinin (BK)], a new, potent and long-acting BK B2 antagonist, were tested in some in vivo models of inflammation. " 06/01/1995 - "Effects of the bradykinin B2 receptor antagonist S 16118 (p-guanidobenzoyl-[Hyp3,Thi5,D-Tic7,Oic8]bradykinin) in different in vivo animal models of inflammation."
4.	Hypotension (Low Blood Pressure) 06/01/1995 - "S 16118 (100 nmol/kg s.c.) prevented the hypotension, the pancreatic edema and the hypovolemia and induced a marked increase in the serum lipase and amylase activity. "
5.	Edema (Dropsy) 06/01/1995 - "S 16118 (100 nmol/kg s.c.) prevented the hypotension, the pancreatic edema and the hypovolemia and induced a marked increase in the serum lipase and amylase activity. "

Related Drugs and Biologics

1.	Bradykinin B2 Receptor
2.	Lipase (Acid Lipase)
3.	Evans Blue (Blue, Evans)
4.	Bradykinin
5.	Amylases

Related Therapies and Procedures

1.	Vagus Nerve Stimulation