Sia(alpha2,3)Gal(beta1,4)GlcNAc alpha-2,8-sialyltransferase

an alpha-2,8-sialyltransferase that exhibits activity toward the Sia(alpha2,3)Gal(beta1,4)GlcNAc sequences of N-linked oligosaccharides; involved in brain development; amino acid sequence given in first source

Also Known As:

ST8Sia III

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Glycosyltransferases: 784
      - Sialyltransferases: 490
        Sia(alpha2,3)Gal(beta1,4)GlcNAc alpha-2,8-sialyltransferase: 1

Related Diseases

1.	Neuroblastoma 09/01/1996 - "Although the promoter region lacked an apparent TATA or CCAAT box and potential regulatory motifs, a transfection experiment involving neuroblastoma cells expressing ST8Sia III demonstrated the minimal promoter activity exhibited by the proximal region 418 bp upstream from the ATG codon, which suggests the presence of tissue-specific enhancer elements."

Related Drugs and Biologics

1.	Codon (Codons)